BMP-2 Polyclonal Antibody | Invitrogen PA1-31215 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BMP-2 Polyclonal Antibody

catalog :

PA1-31215

quantity :

100 ug

price :

US 522.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

BMP

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, dot blot

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 7b	Jain S, Krishna Meka S, Chatterjee K. Curcumin eluting nanofibers augment osteogenesis toward phytochemical based bone tissue engineering. Biomed Mater. 2016;11:055007 pubmed
	Filippi A, Constantin A, Alexandru N, Mocanu C, Vlad M, Fenyo I, et al. VLA4-Enhanced Allogeneic Endothelial Progenitor Cell-Based Therapy Preserves the Aortic Valve Function in a Mouse Model of Dyslipidemia and Diabetes. Pharmaceutics. 2022;14: pubmed publisher

product information

Product Type :

Antibody

Product Name :

BMP-2 Polyclonal Antibody

Catalog # :

PA1-31215

Quantity :

100 ug

Price :

US 522.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Dot Blot: 1:2,000, ELISA: 1:2,000, Immunocytochemistry: 1:2,000, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: 1:200-1:500, Western Blot: 1:200

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Bone Morphogenic Proteins (BMP) are members of the TGF-beta superfamily that affect bone and cartilage formation (Hogan 1996, Reddi 1998 and Francis-West et al. 1999). Mature BMPs are 30-38 kDa proteins that assume a TGF-beta -like cysteine knot configuration. Lovostatin increases bone formation by turning on the bmp-2 gene (Mundy et al. 1999). BMPs stimulate the production of specific bone matrix proteins and alter stromal cell and osteoclast proliferation (Macias et al. 1999, Lecanda et al. 1997). BMPs may also be an important factor for development of the viscera, with roles in cell proliferation, apoptosis, differentiation, and morphogenesis (Hogan 1996, Dale and Wardle 1999). BMPs appear to be responsible for normal dorsal/ventral patterning. Like TGF-beta, BMPs bind to a type II receptor, which then recruits the transducing type I receptor unit, activating the Smad protein signaling pathway (Massague 1994, Derynck 1997, Attisano 1993).

Immunogen :

synthetic peptide SEDVLSEFELRLLSM conjugated to KLH, corresponding to amino acids 45-60 of BMP2.

Format :

Liquid

Applications w/Dilutions :

Dot Blot: 1:2,000, ELISA: 1:2,000, Immunocytochemistry: 1:2,000, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: 1:200-1:500, Western Blot: 1:200

Aliases :

2610024H22Rik; AI467020; AL117858; AW546137; BB189135; BDA2; BMP; BMP2; BMP-2; BMP2A; BMP-2A; BMPRII; BMPR-II; Bone morphogenetic; Bone morphogenetic protein; Bone morphogenetic protein 2; bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A); bone morphogenetic protein 2A; H-BMP-2; morphogen

more info or order :

Invitrogen product webpage