This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PKA alpha Polyclonal Antibody
catalog :
PA1-30236
quantity :
100 µg
price :
US 475.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunoprecipitation
product information
Product Type :
Antibody
Product Name :
PKA alpha Polyclonal Antibody
Catalog # :
PA1-30236
Quantity :
100 µg
Price :
US 475.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Bovine, Human, Mouse, Rat
Applications :
Immunoprecipitation: 20-30 µg/mL, Western Blot: 0.5-4 µg/mL
Species :
Bovine, Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
Protein kinase A (PKA, cAMP-dependent protein kinase) is a key element of a ubiquitous signaling pathway important in the cell cycle, cellular communication, memory formation and behavior. PKA is composed of two catalytic (PKAc; Protein Kinase A catalytic subunit) and two regulatory subunits (PKAr). Upon binding cAMP, the complex dissociates to PKAr dimer and two activated PKAc ser/thr protein kinase catalytic monomers. The released PKAc can translocate into the nucleus and exert a regulatory role in the activation of multiple nuclear hormone receptors. However, PKAc-mediated activation of tonicity-dependent gene expression is cAMP independent. Humans express three types of PKAc subunit - PKAc alpha is present in most human tissues, PKAc beta and gamma are tissue-specific, the later is found in testes.
Immunogen :
Synthetic peptide (residues 7-21) based on the human 40 kDa alpha isoform of the catalytic subunit of PKA.
Format :
Liquid
Applications w/Dilutions :
Immunoprecipitation: 20-30 µg/mL, Western Blot: 0.5-4 µg/mL
Aliases :
alternatively spliced; C(s); Calpha; C-alpha-2; C-alpha-S; cAMP-dependent protein kinase catalytic subunit alpha; cAMP-dependent protein kinase catalytic subunit alpha, isoform 1; cAMP-dependent protein kinase catalytic subunit C alpha; cAMP-dependent protein kinase catalytic subunit Calpha1; Cs-PKA; MGC102831; MGC48865; PKA; PKA C-alpha; PKA catalytic subunit alpha; pkac; Pkaca; PKCA1; PKCD; PPNAD4; PRKACA; protein kinase; protein kinase A; protein kinase A alpha; protein kinase A catalytic subunit; protein kinase cAMP-activated catalytic subunit alpha; protein kinase, cAMP dependent, catalytic, alpha; protein kinase, cAMP-dependent, alpha catalytic subunit; protein kinase, cAMP-dependent, catalytic, alpha; sperm cAMP-dependent protein kinase catalytic subunit; sperm cAMP-dependent protein kinase catalytic subunit Cs
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA