This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Complement C3 Polyclonal Antibody
catalog :
PA1-29715
quantity :
1 mL
price :
US 470.00
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
Chinese hamsters, guinea pig, human, mouse, rat, pigs , domestic rabbit
application :
western blot, immunocytochemistry, flow cytometry
citations: 7
Reference
Paul S, Jain S, Gangwar A, Mohanty S, Khan N, Ahmad Y. Quantifying systemic molecular networks affected during high altitude de-acclimatization. Sci Rep. 2023;13:14768 pubmed publisher
Veremeyko T, Jiang R, He M, Ponomarev E. Complement C4-deficient mice have a high mortality rate during PTZ-induced epileptic seizures, which correlates with cognitive problems and the deficiency in the expression of Egr1 and other immediate early genes. Front Cell Neurosci. 2023;17:1170031 pubmed publisher
AlQot H, Rylett R. A novel transgenic mouse model expressing primate-specific nuclear choline acetyltransferase: insights into potential cholinergic vulnerability. Sci Rep. 2023;13:3037 pubmed publisher
Dragi x107 M, Mitrovi x107 N, Ad x17e i x107 M, Nedeljkovi x107 N, Grkovi x107 I. Microglial- and Astrocyte-Specific Expression of Purinergic Signaling Components and Inflammatory Mediators in the Rat Hippocampus During Trimethyltin-Induced Neurodegeneration. ASN Neuro. 2021;13:17590914211044882 pubmed publisher
Mühlig A, Keir L, Abt J, Heidelbach H, Horton R, Welsh G, et al. Podocytes Produce and Secrete Functional Complement C3 and Complement Factor H. Front Immunol. 2020;11:1833 pubmed publisher
Hughes S, Gumas J, Lee R, Rumano M, Berger N, Gautam A, et al. Prolonged intraocular residence and retinal tissue distribution of a fourth-generation compstatin-based C3 inhibitor in non-human primates. Clin Immunol. 2020;214:108391 pubmed publisher
Jakovljevic M, Lavrnja I, Bozic I, Milosevic A, Bjelobaba I, Savic D, et al. Induction of NTPDase1/CD39 by Reactive Microglia and Macrophages Is Associated With the Functional State During EAE. Front Neurosci. 2019;13:410 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Complement C3 Polyclonal Antibody
Catalog # :
PA1-29715
Quantity :
1 mL
Price :
US 470.00
Clonality :
Polyclonal
Host :
Goat
Reactivity :
Baboon, Equine, Guinea Pig, Hamster, Human, Mouse, Non-human primate, Porcine, Rabbit, Rat
Applications :
Flow Cytometry: 1:100, Immunocytochemistry: 1:500, Immunoelectrophoresis: Assay-dependent, Western Blot: 1:1,000
Species :
Baboon, Equine, Guinea Pig, Hamster, Human, Mouse, Non-human primate, Porcine, Rabbit, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
C3 is a key component of the complement system since classical and alternative activation pathways merge at the C3 activation step when C3 is split into C3a and C3b. The molecular mass of C3 is 185 kDa and it consists of two chains (110 kDa and 75 kDa) held together by disulfide bonds.
Immunogen :
Human complement C3
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:100, Immunocytochemistry: 1:500, Immunoelectrophoresis: Assay-dependent, Western Blot: 1:1,000
Aliases :
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; C3d; complement C3; Complement C3 alpha chain; Complement C3 beta chain; complement C3 protein (GPC3) precursor; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3; complement component C3 alpha-chain; complement component C3a; complement component C3b; complement component C3d; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; I79_008227; LOC100060539; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3; Unknown (protein for MGC:134562)
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA