product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Caspase 3 Polyclonal Antibody
catalog :
PA1-29157
quantity :
500 uL
price :
US 514.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, domestic rabbit
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; loading ...; fig 3a
Abdelrazek H, Helmy S, Elsayed D, Ebaid H, Mohamed R. Ameliorating effects of green tea extract on cadmium induced reproductive injury in male Wistar rats with respect to androgen receptors and caspase- 3. Reprod Biol. 2016;16:300-308 pubmed publisher
Dewi F, Shoukat N, Alifiyah N, Wahyuningsih S, Rosyidah A, Prenggono M, et al. Increasing the effect of annonacin using nanodiamonds to inhibit breast cancer cells growth in rats (Rattus norvegicus)-Induced breast cancer. Heliyon. 2022;8:e11418 pubmed publisher
Masoud S, Kishta A, Canisso I, Abdel Megeid N, Fathalla S, Shawky S, et al. Age-related changes in testicular morphometry and function in Egyptian donkeys. Reprod Domest Anim. 2022;57:1319-1326 pubmed publisher
Singh A, Sarkar D, Singh S. Effect of Trigonella foenum-graecum L. seed extract on the reproductive system of male mice and possible mechanism of its action on spermatogenesis. Andrologia. 2022;54:1643-1659 pubmed publisher
Saeed Ali M, Mohamed Hussein R, Ahmed Kandeil M. The Pro-Oxidant, Apoptotic and Anti-Angiogenic Effects of Selenium Supplementation on Colorectal Tumors Induced by 1,2-Dimethylhydrazine in BALB/C Mice. Rep Biochem Mol Biol. 2019;8:216-226 pubmed
Singh S, Singh S. Chronic exposure to perfluorononanoic acid impairs spermatogenesis, steroidogenesis and fertility in male mice. J Appl Toxicol. 2019;39:420-431 pubmed publisher
Abdel Rahman H, Abdelrazek H, Zeidan D, Mohamed R, Abdelazim A. Lycopene: Hepatoprotective and Antioxidant Effects toward Bisphenol A-Induced Toxicity in Female Wistar Rats. Oxid Med Cell Longev. 2018;2018:5167524 pubmed publisher
Sarkar D, Singh S. Neonatal hypothyroidism affects testicular glucose homeostasis through increased oxidative stress in prepubertal mice: effects on GLUT3, GLUT8 and Cx43. Andrology. 2017;5:749-762 pubmed publisher
Abd Elrazek A, Ahmed Farid O. Protective effect of L-carnitine and L-arginine against busulfan-induced oligospermia in adult rat. Andrologia. 2018;50: pubmed publisher
product information
Product Type :
Antibody
Product Name :
Caspase 3 Polyclonal Antibody
Catalog # :
PA1-29157
Quantity :
500 uL
Price :
US 514.00
Clonality :
Polyclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human, Mouse, Rabbit, Rat
Applications :
Immunohistochemistry (Paraffin): 1:1,000, Immunoprecipitation: 1:2,000, Western Blot: 1:500
Species :
Human, Mouse, Rabbit, Rat
Isotype :
IgG
Storage :
4 C, do not freeze
Description :
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Immunogen :
Recombinant full length human caspase 3 protein.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:1,000, Immunoprecipitation: 1:2,000, Western Blot: 1:500
Aliases :
A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA