Complement C4b/C4c Polyclonal Antibody, FITC | Invitrogen PA1-28407 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Complement C4b/C4c Polyclonal Antibody, FITC

catalog :

PA1-28407

quantity :

500 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

FITC

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Geno K, Spencer B, Bae S, Nahm M. Ficolin-2 binds to serotype 35B pneumococcus as it does to serotypes 11A and 31, and these serotypes cause more infections in older adults than in children. PLoS ONE. 2018;13:e0209657 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Complement C4b/C4c Polyclonal Antibody, FITC

Catalog # :

PA1-28407

Quantity :

500 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

IgG fraction

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:50-1:100

Species :

Human

Isotype :

IgG

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.

Immunogen :

C4c complement isolated from complement activated human serum.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50-1:100

Aliases :

Acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; c4 complement; C4A; C4a anaphylatoxin; C4A2; C4A3; C4A4; C4A6; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4d-A; C4d-B; C4F; C4S; CH; Chido form of C4; CO4; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement component 4B (Chido blood group); CPAMD2; CPAMD3; DAMC-258G8.6; MGC164979; RG