CRP Polyclonal Antibody, HRP | Invitrogen PA1-28329 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CRP Polyclonal Antibody, HRP

catalog :

PA1-28329

quantity :

1 mg

price :

US 380

clonality :

polyclonal

host :

goat

conjugate :

HRP

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

CRP Polyclonal Antibody, HRP

Catalog # :

PA1-28329

Quantity :

1 mg

Price :

US 380

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Goat

Reactivity :

Human

Applications :

ELISA: 1:10,000-1:100,000, Western Blot: 1:1000-1:30,000

Species :

Human

Isotype :

IgG

Storage :

4° C, do not freeze

Description :

CRP (C-reactive protein) is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. Eeach subunit is made up of 206 amino acids, and has a molecular weight of 24 kDa. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.), plays an important role in innate immunity, and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. CRP is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host, and initiates pathogen elimination by interacting with humoral and cellular effector systems in the blood. Patients with elevated basal levels of CRP have been shown to be an increased risk for hypertension and cardiovascular disease.

Immunogen :

Human CRP - detail information is considered to be commercially sensitive

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000-1:100,000, Western Blot: 1:1000-1:30,000

Aliases :

MGC149895, MGC88244, PTX1