ATG8 Polyclonal Antibody | Invitrogen PA1-26648 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ATG8 Polyclonal Antibody

catalog :

PA1-26648

quantity :

250 ug

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Saccharomyces cerevisiae S288C

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

ATG8 Polyclonal Antibody

Catalog # :

PA1-26648

Quantity :

250 ug

Price :

US 474.00

Clonality :

Polyclonal

Purity :

IgG fraction

Host :

Rabbit

Reactivity :

Yeast

Applications :

ELISA: 1:20,000-1:100,000, Western Blot: 1:4,000-1:8,000

Species :

Yeast

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Ubiquitin-like proteins fall into two classes: the first class, ubiquitin-like modifiers (UBLs) function as modifiers in a manner analogous to that of ubiquitin. Examples of UBLs are SUMO, Rub1 (also called Nedd8), Apg8 and Apg12. Proteins of the second class include parkin, RAD23 and DSK2, are designated ubiquitin-domain proteins (UDPs). These proteins contain domains that are related to ubiquitin but are otherwise unrelated to each other. In contrast to UBLs, UDPs are not conjugated to other proteins. Apg8 is required for autophagy (intracellular bulk protein degradation) in yeast. Starved yeast cells take up their own cytoplasm into vacuoles through autophagic bodies. Autophagic bodies form a double-membraned structure called the autophagosome, which subsequently fuses with the vacuole/lysosome. This process similar in mammals. Two sets of genes, APG and AUT, have been identified with this process, and are responsible for two ubiquitin-like systems Apg12 and Apg8, respectively. Apg12 is synthesized in its mature form and seems to have one target, Apg5. Almost all Apg12 molecules are conjugated with Apg5.

Immunogen :

Recombinant, full length S. cerevisiae protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:20,000-1:100,000, Western Blot: 1:4,000-1:8,000

Aliases :

APG8; ATG8; AUT7; Autophagy-related protein 8; Autophagy-related ubiquitin-like modifier ATG8; CVT5; Cytoplasm to vacuole targeting protein 5; ubiquitin-like protein ATG8; YBL0732; YBL078C