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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Collagen I Polyclonal Antibody
catalog :
PA1-26204
quantity :
100 ug
price :
US 514.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 4b, 4d
Baik J, Park H, Kataru R, Savetsky I, Ly C, Shin J, et al. TGF-β1 mediates pathologic changes of secondary lymphedema by promoting fibrosis and inflammation. Clin Transl Med. 2022;12:e758 pubmed publisher
Patricelli C, Lehmann P, Oxford J, Pu X. Doxorubicin-induced modulation of TGF-β signaling cascade in mouse fibroblasts: insights into cardiotoxicity mechanisms. Sci Rep. 2023;13:18944 pubmed publisher
Abdallah H, Koshak A, Farag M, El Sayed N, Badr Eldin S, Ahmed O, et al. Taif Rose Oil Ameliorates UVB-Induced Oxidative Damage and Skin Photoaging in Rats via Modulation of MAPK and MMP Signaling Pathways. ACS Omega. 2023;8:33943-33954 pubmed publisher
Hanetseder D, Levstek T, Teuschl Woller A, Frank J, Schaedl B, Redl H, et al. Engineering of extracellular matrix from human iPSC-mesenchymal progenitors to enhance osteogenic capacity of human bone marrow stromal cells independent of their age. Front Bioeng Biotechnol. 2023;11:1214019 pubmed publisher
McCarthy G, Di Niro R, Finan J, Jain A, Guo Y, Wyatt C, et al. Deletion of the mRNA stability factor ELAVL1 (HuR) in pancreatic cancer cells disrupts the tumor microenvironment integrity. NAR Cancer. 2023;5:zcad016 pubmed publisher
C xe1 ceres Ayala C, Mira R, Acu xf1 a M, Brandan E, Cerpa W, Rebolledo D. Episodic Binge-like Ethanol Reduces Skeletal Muscle Strength Associated with Atrophy, Fibrosis, and Inflammation in Young Rats. Int J Mol Sci. 2023;24: pubmed publisher
Ye J, Li L, Hao R, Gong M, Wang T, Song J, et al. Phase-change composite filled natural nanotubes in hydrogel promote wound healing under photothermally triggered drug release. Bioact Mater. 2023;21:284-298 pubmed publisher
Caliogna L, Bina V, Brancato A, Gastaldi G, Annunziata S, Mosconi M, et al. The Role of PEMFs on Bone Healing: An In Vitro Study. Int J Mol Sci. 2022;23: pubmed publisher
Magallanes J, Liu N, Zhang J, Ouyang Y, Mkaratigwa T, Bian F, et al. A new mouse model of post-traumatic joint injury allows to identify the contribution of Gli1+ mesenchymal progenitors in arthrofibrosis and acquired heterotopic endochondral ossification. Front Cell Dev Biol. 2022;10:954028 pubmed publisher
Fang C, Chen S, Huang C, Liao Y, Chao S, Yu C. Fucoidan-Mediated Inhibition of Fibrotic Properties in Oral Submucous Fibrosis via the MEG3/miR-181a/Egr1 Axis. Pharmaceuticals (Basel). 2022;15: pubmed publisher
Kovacs I, Bugyik E, Dezso K, Tárnoki Zách J, Mehes E, Gulyás M, et al. Malignant pleural mesothelioma nodules remodel their surroundings to vascularize and grow. Transl Lung Cancer Res. 2022;11:991-1008 pubmed publisher
Zhao H, Yang H, Geng C, Chen Y, Tang Y, Li Z, et al. Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p. Theranostics. 2021;11:7600-7615 pubmed publisher
Malakpour Permlid A, Buzzi I, Hegardt C, Johansson F, Oredsson S. Identification of extracellular matrix proteins secreted by human dermal fibroblasts cultured in 3D electrospun scaffolds. Sci Rep. 2021;11:6655 pubmed publisher
Farooqi H, Kang B, Khalid M, Salih A, Hyun K, Park S, et al. Real-time monitoring of liver fibrosis through embedded sensors in a microphysiological system. Nano Converg. 2021;8:3 pubmed publisher
Wörsdörfer P, Rockel A, Alt Y, Kern A, Ergun S. Generation of Vascularized Neural Organoids by Co-culturing with Mesodermal Progenitor Cells. STAR Protoc. 2020;1:100041 pubmed publisher
Yue Y, Yin W, Yang Q, Ren J, Tan L, Wang J, et al. Inhibition of Cathepsin K Alleviates Autophagy-Related Inflammation in Periodontitis-Aggravating Arthritis. Infect Immun. 2020;88: pubmed publisher
Ghiroldi A, Piccoli M, Creo P, Cirillo F, Rota P, D Imperio S, et al. Role of sialidase Neu3 and ganglioside GM3 in cardiac fibroblasts activation. Biochem J. 2020;477:3401-3415 pubmed publisher
Gioscia Ryan R, Clayton Z, Fleenor B, Eng J, Johnson L, Rossman M, et al. Late-life voluntary wheel running reverses age-related aortic stiffness in mice: a translational model for studying mechanisms of exercise-mediated arterial de-stiffening. GeroScience. 2020;: pubmed publisher
Moore M, Bonvallet P, Damaraju S, Modi H, Gandhi A, McFetridge P. Biological characterization of dehydrated amniotic membrane allograft: Mechanisms of action and implications for wound care. J Biomed Mater Res B Appl Biomater. 2020;108:3076-3083 pubmed publisher
Chen X, Zhang W, Zhang Q, Song T, Yu Z, Li Z, et al. NSM00158 Specifically Disrupts the CtBP2-p300 Interaction to Reverse CtBP2-Mediated Transrepression and Prevent the Occurrence of Nonunion. Mol Cells. 2020;43:517-529 pubmed publisher
Stein S, Weber J, Nusser Stein S, Pahla J, Zhang H, Mohammed S, et al. Deletion of fibroblast activation protein provides atheroprotection. Cardiovasc Res. 2021;117:1060-1069 pubmed publisher
Lin F, Zeng Z, Song Y, Li L, Wu Z, Zhang X, et al. YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT. Stem Cell Res Ther. 2019;10:263 pubmed publisher
Buken C, Sahana J, Corydon T, Melnik D, Bauer J, Wehland M, et al. Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity. Sci Rep. 2019;9:11882 pubmed publisher
Derr K, Zou J, Luo K, Song M, Sittampalam G, Zhou C, et al. Fully 3D Bioprinted Skin Equivalent Constructs with Validated Morphology and Barrier Function. Tissue Eng Part C Methods. 2019;: pubmed publisher
Milara J, Peiró T, Serrano A, Artigues E, Aparicio J, Tenor H, et al. Simvastatin Increases the Ability of Roflumilast N-oxide to Inhibit Cigarette Smoke-Induced Epithelial to Mesenchymal Transition in Well-differentiated Human Bronchial Epithelial Cells in vitro. COPD. 2015;12:320-31 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Collagen I Polyclonal Antibody
Catalog # :
PA1-26204
Quantity :
100 ug
Price :
US 514.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Bovine, Human, Mouse, Rat
Applications :
ELISA: 1:5,000-1:50,000, Immunohistochemistry (Paraffin): 1:50-1:200, Immunoprecipitation: 1:100, Western Blot: 1:1,000-1:10,000
Species :
Bovine, Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Collagen I is a Type I collagen with a triple helix structure comprised of two alpha-1 chains and one alpha-2 chain. Collagen I is a member of group I collagen (fibril-forming collagen) found in most connective tissues, and is abundant in bone, cornea, dermis and tendon. Mutations in the COL1A2 gene encoding the alpha-2 chain are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in the COL1A2 gene which codes for the alpha-2 chain, however, tend to be less severe than mutations in the COL1A1 gene, reflecting the different role of alpha-2 chains in matrix integrity. Reciprocal translocations between chromosomes 17 and 22, where Collagen Type 1 genes and the gene for platelet derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified.
Immunogen :
Collagen type I extracted and purified from human and bovine placenta by limited pepsin digestion and selective salt precipitation.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:5,000-1:50,000, Immunohistochemistry (Paraffin): 1:50-1:200, Immunoprecipitation: 1:100, Western Blot: 1:1,000-1:10,000
Aliases :
AA960264; AI325291; alpha 1 type I collagen; alpha 2 type I collagen; alpha 2 type I procollagen; alpha 2(I) collagen; alpha 2(I) procollagen; alpha 2(I)-collagen; alpha1 chain of type I collagen; alpha-1 collagen (I); alpha-1 type 1 collagen; alpha-1 type I collagen; alpha-1 type-1 collagen; alpha1(I) procollagen; alpha2 chain of type I collagen; alpha-2 type I collagen; alpha-2(1) collagen; alpha2(I) collagen; COL1; Col1a1; Col1a-1; COL1A1; matrix protein; Col1a2; Col1a-2; COLA; Cola1; Cola-1; Cola2; Cola-2; COLIA1; collagen; collagen 1 alpha 2 chain; collagen a2; collagen alpha 1 chain type I; collagen alpha 2(I) chain precursor; collagen alpha-1 chain; collagen alpha-1 chain precursor; collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; collagen alpha-2; collagen alpha-2 chain precursor; collagen alpha-2(I) chain; collagen COL1A2; collagen I alpha-2 polypeptide; collagen I, alpha-2 polypeptide; collagen of skin, tendon and bone, alpha-1 chain; collagen of skin, tendon and bone, alpha-2 chain; collagen type I alpha 1; collagen type I alpha 1 chain; collagen type I alpha 2 chain; collagen, type 1, alpha 1; collagen, type I, alpha 1; collagen, type I, alpha 2; EDSC; Mov13; Mov-13; OI1; OI2; OI3; OI4; oim; osteogenesis imperfecta; precollagen alpha-2; prepro-alpha-1 collagen type I; pro-alpha-1 collagen type 1; procollagen type I, alpha 1; procollagen, type 1, alpha 1; procollagen, type I, alpha 1; procollagen, type I, alpha 2; similar to pro alpha 1(I) collagen; Type I Collagen; type I collagen alpha 1 chain; type I collagen alpha1; type I collagen alpha-2 chain; type I collagen pre-pro-alpha1(I) chain; type I proalpha 1; type I procollagen; type I procollagen alpha 1 chain; type I-alpha 1 collagen
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA