Biliverdin Reductase Polyclonal Antibody | Invitrogen PA1-26089 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Biliverdin Reductase Polyclonal Antibody

catalog :

PA1-26089

quantity :

50µL

price :

425.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Chinese hamsters, human, mouse, rat, pigs

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

Biliverdin Reductase Polyclonal Antibody

Catalog # :

PA1-26089

Quantity :

50µL

Price (USD) :

425.00 USD

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Hamster, Human, Mouse, Porcine, Rat

Applications :

Immunohistochemistry (Paraffin): 1-10 µg/mL, Western Blot: 1-5 µg/mL

Species :

Hamster, Human, Mouse, Porcine, Rat

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Biliverdin reductase (BLVR) is a ubiquitously expressed, small cytoplasmic oxidoreductase that catalyzes the reduction of biliverdin to bilirubin. The first step of this process is catalyzed by heme oxygenase, an enzyme that converts heme to iron, carbon monoxide, and biliverdin. BLVR is unique among all enzymes to date in being dual pH/dual cofactor-dependent, as it requires NADH (pH 6.7) or NADPH (pH 8.7) as an electron donor. There are two isoforms of BLVR, biliverdin-IX alpha-reductase (BLVRA), the major component of human adult liver, and biliverdin-IX beta-reductase (BLVRB), found predominantly in fetal liver. The product of BLVR, bilirubin, is an important biological antioxidant, however it is also a neurotoxin and the cause of kernicterus. In addition to being an antioxidant, it inhibits kinase activity and the activity of enzymes such as protein kinase C and NADPH oxidase.

Immunogen :

Purified, full length, native rat protein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1-10 µg/mL, Western Blot: 1-5 µg/mL

Aliases :

0610006A11Rik; 2500001N03Rik; Biliverdin reductase A; biliverdin reductase A-like protein; biliverdin-IX alpha-reductase; BLVR; Blvra; BVR; BVR A; BVRA; EC 1.3.1.24; testis tissue sperm-binding protein Li 61n