Osteopontin Polyclonal Antibody | Invitrogen PA1-25152 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Osteopontin Polyclonal Antibody

catalog :

PA1-25152

quantity :

25 ug

price :

US 470.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:100; loading ...; fig 1e	Gago Fuentes R, Bechberger J, Varela Eirin M, Varela Vazquez A, Acea B, Fonseca E, et al. The C-terminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes. Oncotarget. 2016;7:73055-73067 pubmed publisher
	Dai B, Zhu Y, Li X, Liang Z, Xu S, Zhang S, et al. Blockage of Osteopontin-Integrin β3 Signaling in Infrapatellar Fat Pad Attenuates Osteoarthritis in Mice. Adv Sci (Weinh). 2023;10:e2300897 pubmed publisher
	Dai B, Xu J, Li X, Huang L, Hopkins C, Wang H, et al. Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis. Nat Commun. 2022;13:427 pubmed publisher
	Yang H, Graham L, Reagan A, Grabowska W, Schott W, Howell G. Transcriptome profiling of brain myeloid cells revealed activation of Itgal, Trem1, and Spp1 in western diet-induced obesity. J Neuroinflammation. 2019;16:169 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Osteopontin Polyclonal Antibody

Catalog # :

PA1-25152

Quantity :

25 ug

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Goat

Reactivity :

Mouse

Applications :

ELISA: 0.2-0.8 ug/mL, Immunohistochemistry: 5-15 ug/mL, Inhibition Assays: 1-3 ug/mL, Neutralization: 1-3 ug/mL, Western Blot: 0.1-0.2 ug/mL

Species :

Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D.

Immunogen :

Recombinant, full length mouse protein, expressed in NSO cells.

Format :

Liquid

Applications w/Dilutions :

ELISA: 0.2-0.8 ug/mL, Immunohistochemistry: 5-15 ug/mL, Inhibition Assays: 1-3 ug/mL, Neutralization: 1-3 ug/mL, Western Blot: 0.1-0.2 ug/mL

Aliases :

2AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bone sialoprotein 1 (BSPI/BSP1); Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; CALPHA1 fusion; Early T lymphocyte activation 1 (ETA1); early T-lymphocyte activation 1; early T-lymphocyte activation 1 protein; Eta; ETA-1; HGNC:11255; immunoglobulin alpha 1 heavy chain constant region fusion protein; MGC110940; Minopontin; nephropontin; Op; Opn; Opnl; OSP; osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1); secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); Secreted phosphoprotein 1 (SPP1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); SPP1; SPP-1; SPP1/CALPHA1 fusion; unnamed protein product; urinar; urinary stone protein; Uropontin

more info or order :

Invitrogen product webpage