Catenin alpha-1 Polyclonal Antibody | Invitrogen PA1-25081 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Catenin alpha-1 Polyclonal Antibody

catalog :

PA1-25081

quantity :

100 uL

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, Xenopus laevis

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; Xenopus laevis; loading ...; fig 2a	Herbomel G, Hatte G, Roul J, Padilla Parra S, Tassan J, Tramier M. Actomyosin-generated tension on cadherin is similar between dividing and non-dividing epithelial cells in early Xenopus laevis embryos. Sci Rep. 2017;7:45058 pubmed publisher
	Hatte G, Prigent C, Tassan J. Adherens junctions are involved in polarized contractile ring formation in dividing epithelial cells of Xenopus laevis embryos. Exp Cell Res. 2021;402:112525 pubmed publisher
	Hatte G, Prigent C, Tassan J. Tight junctions negatively regulate mechanical forces applied to adherens junctions in vertebrate epithelial tissue. J Cell Sci. 2018;131: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Catenin alpha-1 Polyclonal Antibody

Catalog # :

PA1-25081

Quantity :

100 uL

Price :

US 474.00

Clonality :

Polyclonal

Purity :

IgG fraction

Host :

Rabbit

Reactivity :

Canine, Human, Mouse, Rat, Xenopus laevis

Applications :

Immunocytochemistry: 1:200, Western Blot: 1:1,000

Species :

Canine, Human, Mouse, Rat, Xenopus laevis

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherence junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

Immunogen :

Synthetic peptide, conjugated to KLH, corresponding to residues E(873) K Q D E T Q T K I K R A S Q(887) of human alpha 1 Catenin.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:200, Western Blot: 1:1,000

Aliases :

[a]E-catenin; 102 kDa cadherin-associated protein; 2010010M04Rik; AA517462; AI988031; alpha E catenin; alpha E-catenin; alpha(E)-catenin; alpha-E-catenin; cadherin associated protein; Cadherin-associated protein; CAP102; catenin (cadherin associated protein), alpha 1; catenin (cadherin-associated protein), alpha; catenin (cadherin-associated protein), alpha 1; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha 1; catenin alpha 1 S homeolog; catenin alpha-1; catenin, alpha 1; Catna1; cell-adhesion protein alphaE catenin; ctnna; ctnna1; ctnna1.S; MDPT2; Renal carcinoma antigen NY-REN-13; XELAEV_18020018mg

more info or order :

Invitrogen product webpage