Cofilin Polyclonal Antibody | Invitrogen PA1-24931 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cofilin Polyclonal Antibody

catalog :

PA1-24931

quantity :

50 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 2

Reference
Burat B, Faucher Q, x10c echov xe1 P, Arnion H, Di Meo F, Sauvage F, et al. Cyclosporine A inhibits MRTF-SRF signaling through Na+/K+ ATPase inhibition and actin remodeling. FASEB Bioadv. 2019;1:561-578 pubmed publisher
Burat B, Gonzalez J, Sauvage F, Aouad H, Arnion H, Pinault E, et al. Sum of peak intensities outperforms peak area integration in iTRAQ protein expression measurement by LC-MS/MS using a TripleTOF 5600+ platform. Biosci Rep. 2019;: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cofilin Polyclonal Antibody

Catalog # :

PA1-24931

Quantity :

50 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

IgG fraction

Host :

Rabbit

Reactivity :

Canine, Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:1,000, Immunohistochemistry: Assay-dependent, Western Blot: 1:10,000

Species :

Canine, Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.

Immunogen :

Synthetic peptide, conjugated to maleimide-activated KLH, corresponding to residues 154-166 of human cofilin with an N-terminal added cysteine.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:1,000, Immunohistochemistry: Assay-dependent, Western Blot: 1:10,000

Aliases :

18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18