P2X2 Polyclonal Antibody | Invitrogen PA1-24623 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

P2X2 Polyclonal Antibody

catalog :

PA1-24623

quantity :

50µL

price :

US 390

clonality :

polyclonal

host :

guinea-pigs

conjugate :

nonconjugated

reactivity :

guinea pig, human, mouse, rat, swine

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

product information

Product Type :

Antibody

Product Name :

P2X2 Polyclonal Antibody

Catalog # :

PA1-24623

Quantity :

50µL

Price :

US 390

Clonality :

Polyclonal

Host :

Guinea Pig

Reactivity :

Guinea Pig, Human, Mouse, Porcine, Rat

Applications :

Immunocytochemistry: 1:500, Immunofluorescence: 1:500, Immunohistochemistry (Frozen): 1:500, Western Blot: 1:500

Species :

Guinea Pig, Human, Mouse, Porcine, Rat

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

P2rx2 are members of the ligand-gated ion channel family that open in response to extracellular ATP. Each receptor is made up of a trimer of subunits (P2X1-7) all of which share the common structure of two transmembrane domains. P2rx2 functions as a ligand-gated ion channel and binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for P2rx2. P2rx2 is involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, P2rx2 regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. P2rx2 also mediates synaptic transmission between neurons and from neurons to smooth muscle. Diseases associated with P2RX2 include Deafness, Autosomal Dominant 41 and Dfna41 Nonsyndromic Hearing Loss And Deafness.

Immunogen :

Synthetic peptide corresponding to residues D(460) S T S T D P K G L A Q L(472) of rat P2X2.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:500, Immunofluorescence: 1:500, Immunohistochemistry (Frozen): 1:500, Western Blot: 1:500

Aliases :

MGC129601, P2X2