Ki-67 Polyclonal Antibody | Invitrogen PA1-21520 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Ki-67 Polyclonal Antibody

catalog :

PA1-21520

quantity :

500 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; loading ...; fig 1e	Burgy O, Bellaye P, Causse S, Beltramo G, Wettstein G, Boutanquoi P, et al. Pleural inhibition of the caspase-1/IL-1? pathway diminishes profibrotic lung toxicity of bleomycin. Respir Res. 2016;17:162 pubmed
	Kalafatakis I, Patellis A, Charalampopoulos I, Gravanis A, Karagogeos D. The beneficial role of the synthetic microneurotrophin BNN20 in a focal demyelination model. J Neurosci Res. 2021;99:1474-1495 pubmed publisher
	Lorente M, García Casas A, Salvador N, Martínez López A, Gabicagogeascoa E, Velasco G, et al. Inhibiting SUMO1-mediated SUMOylation induces autophagy-mediated cancer cell death and reduces tumour cell invasion via RAC1. J Cell Sci. 2019;132: pubmed publisher
	Wang H, He X, Lei T, Liu Y, Huai G, Sun M, et al. Mangiferin induces islet regeneration in aged mice through regulating p16INK4a. Int J Mol Med. 2018;41:3231-3242 pubmed publisher
	Patel P, Tsiperson V, Gottesman S, Somma J, Blain S. Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells. Mol Cancer Res. 2018;16:361-377 pubmed publisher
	Nie D, Wang Z, Zhang Y, Pang D, Ouyang H, Li L. Fat-1 gene inhibits human oral squamous carcinoma cell proliferation through downregulation of Î²-catenin signaling pathways. Exp Ther Med. 2016;11:191-196 pubmed

product information

Product Type :

Antibody

Product Name :

Ki-67 Polyclonal Antibody

Catalog # :

PA1-21520

Quantity :

500 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 10 ug/mL, Immunohistochemistry (Paraffin): 10-20 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

4 C, do not freeze

Description :

Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.

Immunogen :

Synthetic peptide from the human Ki-67 antigen.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 10 ug/mL, Immunohistochemistry (Paraffin): 10-20 ug/mL

Aliases :

antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05

more info or order :

Invitrogen product webpage