This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Aromatase Polyclonal Antibody
catalog :
PA1-21398
quantity :
50 µg
price :
US 470
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, chicken, bovine, pigs , domestic rabbit, domestic horse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 11
Reference
Wang J, Pratap U, Lu Y, Sareddy G, Tekmal R, Vadlamudi R, et al. Development and Characterization of Inducible Astrocyte-Specific Aromatase Knockout Mice. Biology (Basel). 2023;12: pubmed publisher
Ricci G, Guillou F, Catizone A, Mele V, Moggio M, Chioccarelli T, et al. KISS1R and ANKRD31 Cooperate to Enhance Leydig Cell Gene Expression via the Cytoskeletal-Nucleoskeletal Pathway. Front Cell Dev Biol. 2022;10:877270 pubmed publisher
Bevilacqua A, Dragotto J, Lucarelli M, Di Emidio G, Monastra G, Tatone C. High Doses of D-Chiro-Inositol Alone Induce a PCO-Like Syndrome and Other Alterations in Mouse Ovaries. Int J Mol Sci. 2021;22: pubmed publisher
Kurowska P, Mlyczy x144 ska E, Dawid M, Grzesiak M, Dupont J, Rak A. The role of vaspin in porcine corpus luteum. J Endocrinol. 2020;247:283-294 pubmed publisher
Armasu I, Preda C, Ianole V, Mocanu V, Hristov I, Andriescu E, et al. INSIGHTS ON AROMATASE IMMUNOHISTOCHEMISTRY: VARIATIONS BETWEEN INTRINSIC MOLECULAR SUBTYPES OF BREAST CANCERS. Acta Endocrinol (Buchar). 2020;16:22-29 pubmed publisher
Kurowska P, Mlyczy x144 ska E, Dawid M, Dupont J, Rak A. Role of vaspin in porcine ovary: effect on signaling pathways and steroid synthesis via GRP78 receptor and protein kinase A†. Biol Reprod. 2020;102:1290-1305 pubmed publisher
Su Y, Du G, Shen H, Wang W, Bao J, Aierken A, et al. Increased expression of aromatase cytochrome P450 enzyme is associated with prolactinoma invasiveness in post-menopausal women. J Int Med Res. 2019;47:3115-3126 pubmed publisher
Jin J, Hu Q, Xu W, Zhu W, Liu B, Liu J, et al. Tanshinone IIA attenuates estradiol-induced polycystic ovarian syndrome in mice by ameliorating FSHR expression in the ovary. Exp Ther Med. 2019;17:3501-3508 pubmed publisher
Puttabyatappa M, Martin J, Andriessen V, Stevenson M, Zeng L, Pennathur S, et al. Developmental programming: Changes in mediators of insulin sensitivity in prenatal bisphenol A-treated female sheep. Reprod Toxicol. 2019;85:110-122 pubmed publisher
Puttabyatappa M, Lu C, Martin J, Chazenbalk G, DUMESIC D, Padmanabhan V. Developmental Programming: Impact of Prenatal Testosterone Excess on Steroidal Machinery and Cell Differentiation Markers in Visceral Adipocytes of Female Sheep. Reprod Sci. 2018;25:1010-1023 pubmed publisher
Selek A, Cetinarslan B, Gurbuz Y, Tarkun I, Canturk Z, Cabuk B. Aromatase enzyme expression in acromegaly and its possible relationship with disease prognosis. Endocrine. 2015;49:250-7 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Aromatase Polyclonal Antibody
Catalog # :
PA1-21398
Quantity :
50 µg
Price :
US 470
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Bovine, Chicken, Equine, Human, Mouse, Porcine, Rabbit, Rat
Applications :
Immunohistochemistry (Paraffin): 10-20 µg/mL, Western Blot: 0.5-4 µg/mL
Species :
Bovine, Chicken, Equine, Human, Mouse, Porcine, Rabbit, Rat
Isotype :
IgG
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
Immunogen :
Synthetic peptide surrounding amino acid 385 of human Aromatase
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 10-20 µg/mL, Western Blot: 0.5-4 µg/mL
Aliases :
Ar; ArKO; ARO; ARO1; Arom; Aromatase; aromatase 1; aromatase cytochrome P450; aromatase cytochrome P450 19A1; CPV1; CYAR; Cyp19; Cyp19a; Cyp19a1; CYP19P1; CYPXIX; CYPXIXA1; Cytochrome P450 17-alpha; cytochrome P450 19 type I; Cytochrome P450 19A1; cytochrome P450 aromatase; cytochrome P-450 aromatase; cytochrome P-450 aromatase (alt.); cytochrome P450 family 19 subfamily a; cytochrome P450 family 19 subfamily A member 1; Cytochrome P450, 19, aromatase; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, family 19, subfamily A, polypeptide 1; cytochrome P450, family XIX (conversion of androgen to estrogen), aromatase; cytochrome P450, family19, subfamily A, polypeptide 1; cytochrome P450, subfamily 19; cytochrome P450, subfamily XIX (aromatization of androgens); cytochrome P-450AROM; estrogen synthase; estrogen synthetase; flavoprotein-linked monooxygenase; Int5; Int-5; MGC104309; microsomal monooxygenase; P450AROM; P-450AROM; type III cytochrome p450 aromatase
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA