product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
THRA Polyclonal Antibody
catalog :
PA1-211A
quantity :
100 uL
price :
US 451.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3b
Ohba K, Sinha R, Singh B, Iannucci L, Zhou J, Kovalik J, et al. Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model. Thyroid. 2017;27:852-860 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 3a
  • western blot; human; 1:1000; loading ...; fig s5b
Cvoro A, Bajić A, Zhang A, Simon M, Golic I, Sieglaff D, et al. Ligand Independent and Subtype-Selective Actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells. PLoS ONE. 2016;11:e0164407 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5a
  • western blot; mouse; 1:1000; loading ...; fig 4b
Sarkar D, Singh S. Effect of neonatal hypothyroidism on prepubertal mouse testis in relation to thyroid hormone receptor alpha 1 (THR?1). Gen Comp Endocrinol. 2017;251:109-120 pubmed publisher
  • western blot; mouse; 1:500; fig 5
Wadosky K, Berthiaume J, Tang W, Zungu M, Portman M, Gerdes A, et al. MuRF1 mono-ubiquitinates TRα to inhibit T3-induced cardiac hypertrophy in vivo. J Mol Endocrinol. 2016;56:273-90 pubmed publisher
  • western blot; rat; fig 5
Campo Verde Arboccó F, Sasso C, Actis E, Carón R, Hapon M, Jahn G. Hypothyroidism advances mammary involution in lactating rats through inhibition of PRL signaling and induction of LIF/STAT3 mRNAs. Mol Cell Endocrinol. 2016;419:18-28 pubmed publisher
Sarkar D, Jaiswal A, Singh S. Ontogeny of TRα1 expression in the mouse testis and epididymis during postnatal development. Andrologia. 2022;54:e14507 pubmed publisher
Than A, Xu S, Li R, Leow M, Sun L, Chen P. Angiotensin type 2 receptor activation promotes browning of white adipose tissue and brown adipogenesis. Signal Transduct Target Ther. 2017;2:17022 pubmed publisher
Yu G, Tzouvelekis A, Wang R, Herazo Maya J, Ibarra G, Srivastava A, et al. Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function. Nat Med. 2018;24:39-49 pubmed publisher
Yao J, Jia L, Khan N, Lin C, Mitter S, Boulton M, et al. Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium. Autophagy. 2015;11:939-53 pubmed publisher
Xie L, Pi X, Townley Tilson W, Li N, Wehrens X, Entman M, et al. PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban. J Clin Invest. 2015;125:2759-71 pubmed publisher
product information
Product Type :
Antibody
Product Name :
THRA Polyclonal Antibody
Catalog # :
PA1-211A
Quantity :
100 uL
Price :
US 451.00
Clonality :
Polyclonal
Host :
Rabbit
Reactivity :
Chicken, Human, Mouse, Rat
Applications :
Gel Shift: 1:10, Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 1:20-1:100, Western Blot: 1:200
Species :
Chicken, Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Immunogen :
Synthetic Peptide: E(403) V F E D Q E V(410)
Format :
Liquid
Applications w/Dilutions :
Gel Shift: 1:10, Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 1:20-1:100, Western Blot: 1:200
Aliases :
6430529J03Rik; AR7; avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 1; AW259572; cerbA protein; c-erb-A protein; c-erb-A thyroid hormone receptor; c-ERBA-1; cerbAalpha; c-erbAalpha; c-erbA-alpha; c-erbAalpha2; c-erbA-alpha2; c-erbAalpha2; thyroid hormone receptor alpha; CHNG6; E ERB-T-1; EAR7; EAR-7; ERBA; ERBA ALPHA; ERBA related 7; ERBA1; ERBA-related 7; ERB-T-1; MGC000261; MGC43240; NR1A1; Nuclear receptor subfamily 1 group A member 1; Oncogene ERBA; Rvr; T3R[a]; T3Ralpha; Thra; THRA1; THRA2; Thyroid hormone receptor alpha; thyroid hormone receptor alpha 1; thyroid hormone receptor alpha 1 (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 1 formerly ERBA1); thyroid hormone receptor alpha 2; thyroid hormone receptor beta; thyroid hormone receptor, alpha; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian); thyroid normone nuclear receptor alpha variant 1; TR; TR alpha 1; TR alpha 1+2; TR alpha 2; triiodothyronine receptor; unnamed protein product; V-erbA-related protein 7
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA