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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ubiquitin Polyclonal Antibody
catalog :
PA1-187
quantity :
100 µg
price :
US 435
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs, Xenopus laevis
application :
western blot
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; Xenopus laevis; fig 1f
Fullbright G, Rycenga H, Gruber J, Long D. p97 Promotes a Conserved Mechanism of Helicase Unloading during DNA Cross-Link Repair. Mol Cell Biol. 2016;36:2983-2994 pubmed publisher
Nguyen Dien G, Kozul K, Cui Y, Townsend B, Kulkarni P, Ooi S, et al. FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors. EMBO J. 2023;42:e112767 pubmed publisher
Shakya V, Barbeau W, Xiao T, Knutson C, Schuler M, Hughes A. A nuclear-based quality control pathway for non-imported mitochondrial proteins. elife. 2021;10: pubmed publisher
Rycenga H, Wolfe K, Yeh E, Long D. Uncoupling of p97 ATPase activity has a dominant negative effect on protein extraction. Sci Rep. 2019;9:10329 pubmed publisher
Lobanova E, Finkelstein S, Li J, Travis A, Hao Y, Klingeborn M, et al. Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration. Nat Commun. 2018;9:1738 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Ubiquitin Polyclonal Antibody
Catalog # :
PA1-187
Quantity :
100 µg
Price :
US 435
Clonality :
Polyclonal
Purity :
Protein G
Host :
Rabbit
Reactivity :
Canine, Human, Mouse, Non-human primate, Rat
Applications :
Western Blot: 1:100-1:1,000
Species :
Canine, Human, Mouse, Non-human primate, Rat
Isotype :
IgG
Storage :
-20°C
Description :
Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.
Immunogen :
Full-length monoubiqutin
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:100-1:1,000
Aliases :
0610006J14Rik; 1810034D23Rik; 2700054O04Rik; 40S ribosomal protein S27a; 40S ribosomal protein S27-like; 40S ribosomal protein S27-like protein; AI194771; AL033289; CEP80; CG5271; CG5271-PA; Chap1; Dmel CG5271; Dmel_CG5271; Dub80; epididymis luminal protein 112; epididymis secretory protein Li 50; HEL112; HEL-S-50; hm:zeh0386; HMG20; hPLIC-2; HRIHFB2157; HUBCEP52; ik:tdsubc_1f2; l(2)04820; l(2)31Ei; LOC100912032; LOC101747587; male female sterile 31; mfs(2)31; mfs(2)48; mfs48; OTTHUMP00000200786; OTTHUMP00000201692; PLIC-2; polyubiquitin; polyubiquitin B; polyubiquitin C; poly-ubiquitin precursor; polyubiquitin-B; Polyubiquitin-C; polyubiquitin-C-like; RE44350p; ribosomal protein S27; ribosomal protein S27 like; ribosomal protein S27A; ribosomal protein S27a L homeolog; ribosomal protein S27a S homeolog; ribosomal protein S27-like; ribosomal protein S27-like protein; RPL40; RpS27; Rps27a; rps27a.L; rps27a.S; RpS27A-PA; RPS27L; S27A; similar to polyubiquitin; similar to ubiquitin-S27a fusion protein; Small ribosomal subunit protein eS27-like; Small ribosomal subunit protein eS31; tdsubc_1f2; TI-225; UB3-D; Uba52; UBA80; UBB; Ubb2; UBC; UBCEP1; UBCEP80; Ubi-f80; Ubi-m; Ubiq; Ubiquilin 2; ubiquitin; ubiquitin (34 AA) (1 is 2nd base in codon); ubiquitin and ribosomal protein S27a; ubiquitin B; ubiquitin C; ubiquitin carboxyl extension protein 80; ubiquitin copy 4; ubiquitin fusion 80; ubiquitin polyprotein (heat shock related); ubiquitin/ribosomal protein; ubiquitin-40S ribosomal protein S27a; ubiquitin-40S ribosomal protein S27a-like; ubiquitin-CEP80; ubiquitin-hybrid protein precursor; Ubiquitin-monomeric; Ubiquitin-related; Ubiquitin-related 1; Ubiquitin-related 2; ubiquitin-S27a fusion protein; Unknown (protein for MGC:127652); unnamed protein product; XELAEV_18028796mg; xx:tdsubc_1f2; zgc:66168; zgc:66168 protein
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA