NFkB p65 Polyclonal Antibody | Invitrogen PA1-186 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NFkB p65 Polyclonal Antibody

catalog :

PA1-186

quantity :

100 µg

price :

US 485

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

Invitrogen product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:400; loading ...; fig 6b western blot; mouse; 1:400; loading ...; fig 6a	Merlo S, Luaces J, Spampinato S, Toro Urrego N, Caruso G, D Amico F, et al. SIRT1 Mediates Melatonin's Effects on Microglial Activation in Hypoxia: In Vitro and In Vivo Evidence. Biomolecules. 2020;10: pubmed publisher
western blot; human; 1:1000; fig 5b	Shi D, Shi G, Xie J, Du X, Yang H. MicroRNA-27a Inhibits Cell Migration and Invasion of Fibroblast-Like Synoviocytes by Targeting Follistatin-Like Protein 1 in Rheumatoid Arthritis. Mol Cells. 2016;39:611-8 pubmed publisher
	Gonz xe1 lez L xf3 pez P, xc1 lvarez Villarreal M, Ruiz Sim xf3 n R, L xf3 pez Pastor A, de Ceniga M, Esparza L, et al. Role of miR-15a-5p and miR-199a-3p in the inflammatory pathway regulated by NF-κB in experimental and human atherosclerosis. Clin Transl Med. 2023;13:e1363 pubmed publisher
	Mhatre Winters I, Eid A, Han Y, Tieu K, Richardson J. Sex and APOE Genotype Alter the Basal and Induced Inflammatory States of Primary Microglia from APOE Targeted Replacement Mice. Int J Mol Sci. 2022;23: pubmed publisher
	Yousef M, Salama M, El Fawal H, Abdelnaser A. Selective GSK3β Inhibition Mediates an Nrf2-Independent Anti-inflammatory Microglial Response. Mol Neurobiol. 2022;59:5591-5611 pubmed publisher
	Gupta S, Hunt J, Adcox H, Andersen S, Gumpf J, Green R, et al. Functional Characterization of Non-Ankyrin Repeat Domains of Orientia tsutsugamushi Ank Effectors Reveals Their Importance for Molecular Pathogenesis. Infect Immun. 2022;90:e0062821 pubmed publisher
	Caruso G, Spampinato S, Costantino G, Merlo S, Sortino M. SIRT1-Dependent Upregulation of BDNF in Human Microglia Challenged with Aβ: An Early but Transient Response Rescued by Melatonin. Biomedicines. 2021;9: pubmed publisher
	Singh A, Devkar R, Basu A. Myeloid Differentiation Primary Response 88-Cyclin D1 Signaling in Breast Cancer Cells Regulates Toll-Like Receptor 3-Mediated Cell Proliferation. Front Oncol. 2020;10:1780 pubmed publisher
	Nassef M, Kopp S, Melnik D, Corydon T, Sahana J, Kruger M, et al. Short-Term Microgravity Influences Cell Adhesion in Human Breast Cancer Cells. Int J Mol Sci. 2019;20: pubmed publisher
	Pan Y, Long X, Yi R, Zhao X. Polyphenols in Liubao Tea Can Prevent CCl₄-Induced Hepatic Damage in Mice through Its Antioxidant Capacities. Nutrients. 2018;10: pubmed publisher
	Chen X, Zhang J, Yi R, Mu J, Zhao X, Yang Z. Hepatoprotective Effects of Lactobacillus on Carbon Tetrachloride-Induced Acute Liver Injury in Mice. Int J Mol Sci. 2018;19: pubmed publisher
	Tan Y, Sansanaphongpricha K, Xie Y, Donnelly C, Luo X, Heath B, et al. Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine. Clin Cancer Res. 2018;24:4242-4255 pubmed publisher
	Boulay A, Gilbert A, Oliveira Moreira V, Blugeon C, Perrin S, Pouch J, et al. Connexin 43 Controls the Astrocyte Immunoregulatory Phenotype. Brain Sci. 2018;8: pubmed publisher
	Ogundele O, Lee C. CaMKIIα expression in a mouse model of NMDAR hypofunction schizophrenia: Putative roles for IGF-1R and TLR4. Brain Res Bull. 2018;137:53-70 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NFkB p65 Polyclonal Antibody

Catalog # :

PA1-186

Quantity :

100 µg

Price :

US 485

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ChIP Assay: 1-5 µg x 10^6 cells, Flow Cytometry: 3-5 µg/1x10^6 cells, Immunocytochemistry: 1-2 µg/mL, Immunoprecipitation: 3 µg, Western Blot: 1-3 µg/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20°C

Description :

Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.

Immunogen :

GLLSGDEDFSSIADMDFS

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 1-5 µg x 10^6 cells, Flow Cytometry: 3-5 µg/1x10^6 cells, Immunocytochemistry: 1-2 µg/mL, Immunoprecipitation: 3 µg, Western Blot: 1-3 µg/mL

Aliases :

avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela

more info or order :

Invitrogen product webpage