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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
beta Actin Polyclonal Antibody
catalog :
PA1-183
quantity :
100 µg
price :
US 385.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Invitrogen product webpage
citations: 52
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig 5c
Yang X, Huo F, Liu B, Liu J, Chen T, Li J, et al. Crocin Inhibits Oxidative Stress and Pro-inflammatory Response of Microglial Cells Associated with Diabetic Retinopathy Through the Activation of PI3K/Akt Signaling Pathway. J Mol Neurosci. 2017;61:581-589 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3
Bingula R, Dupuis C, Pichon C, Berthon J, Filaire M, Pigeon L, et al. Study of the Effects of Betaine and/or C-Phycocyanin on the Growth of Lung Cancer A549 Cells In Vitro and In Vivo. J Oncol. 2016;2016:8162952 pubmed publisher
Kim S, Isberg R. The Sde phosphoribosyl-linked ubiquitin transferases protect the Legionella pneumophila vacuole from degradation by the host. Proc Natl Acad Sci U S A. 2023;120:e2303942120 pubmed publisher
Harper N, Burnside C, Klinge S. Principles of mitoribosomal small subunit assembly in eukaryotes. Nature. 2023;614:175-181 pubmed publisher
Kar F, Hacio x11f lu C, Ka xe7 ar S. The dual role of boron in vitro neurotoxication of glioblastoma cells via SEMA3F/NRP2 and ferroptosis signaling pathways. Environ Toxicol. 2023;38:70-77 pubmed publisher
Moreno Martínez L, Santiago L, de la Torre M, Calvo A, Pardo J, Osta R. Hemizygous Granzyme A Mice Expressing the hSOD1G93A Transgene Show Slightly Extended Lifespan. Int J Mol Sci. 2022;23: pubmed publisher
Parvathaneni V, Chilamakuri R, Kulkarni N, Baig N, Agarwal S, Gupta V. Exploring Amodiaquine's Repurposing Potential in Breast Cancer Treatment-Assessment of In-Vitro Efficacy & Mechanism of Action. Int J Mol Sci. 2022;23: pubmed publisher
Ricci G, Guillou F, Catizone A, Mele V, Moggio M, Chioccarelli T, et al. KISS1R and ANKRD31 Cooperate to Enhance Leydig Cell Gene Expression via the Cytoskeletal-Nucleoskeletal Pathway. Front Cell Dev Biol. 2022;10:877270 pubmed publisher
Wang X, Zhang J, Liao Y, Jin Y, Yu X, Li H, et al. DNMT1-Mediated DNA Methylation Targets CDKN2B to Promote the Repair of Retinal Ganglion Cells in Streptozotocin-Induced Mongolian Gerbils during Diabetic Retinopathy. Comput Math Methods Med. 2022;2022:9212116 pubmed publisher
Abd El Haleim E, Sallam N. Vitamin D modulates hepatic microRNAs and mitigates tamoxifen-induced steatohepatitis in female rats. Fundam Clin Pharmacol. 2022;36:338-349 pubmed publisher
Chowdhury D, Gardner J, Satpati A, Nookala S, Mukundan S, Porollo A, et al. Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity. Front Immunol. 2021;12:755961 pubmed publisher
Piron S, Verhoeven J, De Coster E, Descamps B, Kersemans K, Pieters L, et al. Impact of the molar activity and PSMA expression level on [18F]AlF-PSMA-11 uptake in prostate cancer. Sci Rep. 2021;11:22623 pubmed publisher
Lee J, Lee S, Kim D, Shin N, Jeong S, Yang C, et al. Social isolation-related depression accelerates ethanol intake via microglia-derived neuroinflammation. Sci Adv. 2021;7:eabj3400 pubmed publisher
Ren S, Tan X, Fu M, Ren S, Wu X, Chen T, et al. Downregulation of miR-375 contributes to ERBB2-mediated VEGFA overexpression in esophageal cancer. J Cancer. 2021;12:7138-7146 pubmed publisher
Tan X, Ren S, Fu M, Ren S, Yang C, Wu X, et al. microRNA-196b promotes esophageal squamous cell carcinogenesis and chemoradioresistance by inhibiting EPHA7, thereby restoring EPHA2 activity. Am J Cancer Res. 2021;11:3594-3610 pubmed
Das S, Surve V, Marathe S, Wad S, Karulkar A, Srinivasan S, et al. IL-9 Abrogates the Metastatic Potential of Breast Cancer by Controlling Extracellular Matrix Remodeling and Cellular Contractility. J Immunol. 2021;206:2740-2752 pubmed publisher
Wang D, Hartman R, Han C, Zhou C, Couch B, Malkamaki M, et al. Lactate oxidative phosphorylation by annulus fibrosus cells: evidence for lactate-dependent metabolic symbiosis in intervertebral discs. Arthritis Res Ther. 2021;23:145 pubmed publisher
El Sherbiny M, Atef H, Eladl M, Mohamed A, El Shafey M, Ali H, et al. Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production. Front Pharmacol. 2021;12:631216 pubmed publisher
Vukušić K, Ponjavić I, Buđa R, Risteski P, Tolić I. Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation. Dev Cell. 2021;56:1253-1267.e10 pubmed publisher
Yang M, Chen Y, Tu S, Chi P, Chuang K, Chang C, et al. Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging. Int J Mol Sci. 2021;22: pubmed publisher
Martín Bernabé A, Tarragó Celada J, Cunin V, Michelland S, Cortés R, Poignant J, et al. Quantitative Proteomic Approach Reveals Altered Metabolic Pathways in Response to the Inhibition of Lysine Deacetylases in A549 Cells under Normoxia and Hypoxia. Int J Mol Sci. 2021;22: pubmed publisher
Yamada S, Yassin M, Weigel T, Schmitz T, Hansmann J, Mustafa K. Surface activation with oxygen plasma promotes osteogenesis with enhanced extracellular matrix formation in three-dimensional microporous scaffolds. J Biomed Mater Res A. 2021;109:1560-1574 pubmed publisher
Lee S, Kwon J, Lee K. Bcl2l10 induces metabolic alterations in ovarian cancer cells by regulating the TCA cycle enzymes SDHD and IDH1. Oncol Rep. 2021;45: pubmed publisher
Hu J, Zhao Q, Kong L, Wang J, Yan J, Xia X, et al. Regulation of tumor immune suppression and cancer cell survival by CXCL1/2 elevation in glioblastoma multiforme. Sci Adv. 2021;7: pubmed publisher
Xu Y, Zhang Y, Liang H, Liu X. Coumestrol mitigates retinal cell inflammation, apoptosis, and oxidative stress in a rat model of diabetic retinopathy via activation of SIRT1. Aging (Albany NY). 2021;13:5342-5357 pubmed publisher
Kritschil R, Zhang Z, Lei C, Zhong J, Dong Q, Lee J, et al. Effects of suppressing bioavailability of insulin-like growth factor on age-associated intervertebral disc degeneration. JOR Spine. 2020;3:e1112 pubmed publisher
Ledwaba S, Costa D, Bolick D, Giallourou N, Medeiros P, Swann J, et al. Enteropathogenic Escherichia coli Infection Induces Diarrhea, Intestinal Damage, Metabolic Alterations, and Increased Intestinal Permeability in a Murine Model. Front Cell Infect Microbiol. 2020;10:595266 pubmed publisher
Muhammad R, Sallam N, El Abhar H. Activated ROCK/Akt/eNOS and ET-1/ERK pathways in 5-fluorouracil-induced cardiotoxicity: modulation by simvastatin. Sci Rep. 2020;10:14693 pubmed publisher
Lee S, Kang Y, Kwon J, Nishi Y, Yanase T, Lee K, et al. miR-4463 regulates aromatase expression and activity for 17β-estradiol synthesis in response to follicle-stimulating hormone. Clin Exp Reprod Med. 2020;47:194-206 pubmed publisher
Thomas A, Samykutty A, Gomez Gutierrez J, Yin W, Egger M, McNally M, et al. Actively Targeted Nanodelivery of Echinomycin Induces Autophagy-Mediated Death in Chemoresistant Pancreatic Cancer In Vivo. Cancers (Basel). 2020;12: pubmed publisher
Wilson M, Rajan S, Danoff A, White R, Hensley M, Quinlivan V, et al. A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein. PLoS Genet. 2020;16:e1008941 pubmed publisher
El Ghaiesh S, Bahr H, Ibrahiem A, Ghorab D, Alomar S, Farag N, et al. Metformin Protects From Rotenone-Induced Nigrostriatal Neuronal Death in Adult Mice by Activating AMPK-FOXO3 Signaling and Mitigation of Angiogenesis. Front Mol Neurosci. 2020;13:84 pubmed publisher
Lei C, Colangelo D, Patil P, Li V, Ngo K, Wang D, et al. Influences of circulatory factors on intervertebral disc aging phenotype. Aging (Albany NY). 2020;12:12285-12304 pubmed publisher
Moreno Martínez L, de la Torre M, Muñoz M, Zaragoza P, Aguilera J, Calvo A, et al. Neuroprotective Fragment C of Tetanus Toxin Modulates IL-6 in an ALS Mouse Model. Toxins (Basel). 2020;12: pubmed publisher
Girardi B, Pricci M, Giorgio F, Piazzolla M, Iannone A, Losurdo G, et al. Silymarin, boswellic acid and curcumin enriched dietetic formulation reduces the growth of inherited intestinal polyps in an animal model. World J Gastroenterol. 2020;26:1601-1612 pubmed publisher
Thomas F, Holmes K, Kreuz S, Hillmen P, Lefevre P. DAPK3 participates in the mRNA processing of immediate early genes in chronic lymphocytic leukaemia. Mol Oncol. 2020;14:1268-1281 pubmed publisher
Parvathaneni V, Kulkarni N, Shukla S, Farrales P, Kunda N, Muth A, et al. Systematic Development and Optimization of Inhalable Pirfenidone Liposomes for Non-Small Cell Lung Cancer Treatment. Pharmaceutics. 2020;12: pubmed publisher
Lee S, Kwon J, Woo J, Kim K, Lee K. Bcl2l10 mediates the proliferation, invasion and migration of ovarian cancer cells. Int J Oncol. 2020;56:618-629 pubmed publisher
Tao Y, Chen Q, Wang L, Yang X, Cun Q, Yang W, et al. Pirfenidone suppresses the abnormal activation of human Müller cells after platelet-derived growth factor-BB stimulation. Int J Ophthalmol. 2019;12:1075-1082 pubmed publisher
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Bazzari F, Abdallah D, El Abhar H. Chenodeoxycholic Acid Ameliorates AlCl3-Induced Alzheimer's Disease Neurotoxicity and Cognitive Deterioration via Enhanced Insulin Signaling in Rats. Molecules. 2019;24: pubmed publisher
Powers S, Ryan T, Pak E, Fraser M, McClung J, Hannan J. Chronic high-fat diet decreased detrusor mitochondrial respiration and increased nerve-mediated contractions. Neurourol Urodyn. 2019;38:1524-1532 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
beta Actin Polyclonal Antibody
Catalog # :
PA1-183
Quantity :
100 µg
Price :
US 385.00
Clonality :
Polyclonal
Purity :
Protein G
Host :
Rabbit
Reactivity :
Human, Mouse, Non-human primate, Rat
Applications :
Immunocytochemistry: 1:50-1:200, Immunoprecipitation: 2 µg, Western Blot: 1:500-1:2,000
Species :
Human, Mouse, Non-human primate, Rat
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
Beta actin is one of six actin isoforms which have been identified. Beta actin is a non-muscle cytoskeletal protein in all human cell types and is involved in cell motility, structure, and integrity. There are six different actin isoforms in human. The beta isoform of actin, along with gamma actin, coexist in most cell types as components of the cyto-skeleton. Beta actins are cytoplasmic proteins ubuquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of two stranded helix. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Because beta actin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting. Antibodies to beta-actin provide a specific and useful tool in studying the intracellular distribution of beta-actin and the static and dynamic aspects of the cytoskeleton.
Immunogen :
Purified full-length recombinant human beta-actin expressed in E. coli
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:50-1:200, Immunoprecipitation: 2 µg, Western Blot: 1:500-1:2,000
Aliases :
0610041G09Rik; AA959943; AAT6; ACT; Act4; Act-4; ACT-5; ACTA; acta1; acta1b; ACTA2; Acta-2; ACTA3; actb; actb.L; actb1; actba; ACTC; actc1; Actc-1; actc1b; ACTE; Actg; ACTG1; Actg2; ACTGE; actin; actin alpha 1; actin alpha 1, skeletal muscle; actin alpha 1, skeletal muscle b; actin alpha 2, smooth muscle; actin alpha cardiac; actin alpha cardiac 1; actin alpha cardiac muscle 1; actin alpha cardiac muscle 1b; actin beta; actin gamma 1; actin gamma 2, smooth muscle; actin, alpha 1, skeletal muscle; actin, alpha 1b, skeletal muscle; actin, alpha 2, smooth muscle, aorta; Actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; actin, alpha cardiac muscle 1b; actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, cardiac 1; actin, alpha, cardiac muscle; actin, alpha, cardiac muscle 1; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; actin, beta; actin, beta 1; actin, beta L homeolog; actin, beta, cytoplasmic; actin, cytoplasmic 1; Actin, cytoplasmic 1, N-terminally processed; Actin, cytoplasmic 2; Actin, cytoplasmic 2, N-terminally processed; actin, gamma 1; actin, gamma 2, smooth muscle, enteric; actin, gamma, cytoplasmic 1; actin, gamma-enteric smooth muscle; Actin, gamma-enteric smooth muscle, intermediate form; actin-like protein; Actl; ACTL3; Acts; ACTSA; ACTSG; Actsk-1; Actvs; Actx; AL023024; alpha actin 1; alpha-actin cardiac; alpha-actin-1; Alpha-actin-2; alpha-actin-3; alphac-actin; Alpha-cardiac actin; alphaSMA; alpha-smooth muscle actin; ASD5; ASMA; a-SMA; Bact; Bact; actin; B-actin; bactin1; bactin1 protein; bactzf; B-ACTZF; beta actin; beta cytoskeletal actin; beta-actin; beta-actin FE-3; beta-actin-1; BRWS1; BRWS2; cardiac muscle alpha actin 1; cardiofunk; cell growth-inhibiting gene 46 protein; Cfk; CFTD; CFTD1; CFTDM; CMD1R; CMH11; cytoplasmic 1; cytoplasmic beta-actin; cytoskeletal beta actin; cytoskeletal gamma-actin; cytoskeletal protein; deafness, autosomal dominant 20; deafness, autosomal dominant 26; DFNA20; DFNA26; E430023M04Rik; E51; epididymis luminal protein 176; fa27h01; fb83f06; gamma non-muscle actin; gamma-2-actin; Gamma-actin; gamma-enteric smooth muscle actin; GIG46; HEL-176; hm:zeh0631; I79_002310; I79_013242; I79_019066; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; nemaline myopathy type 3; PS1TP5-binding protein 1; PS1TP5BP1; SHPM; similar to beta actin; skeletal alpha actin; skeletal alpha1 actin; sma; SMalphaA; SMGA; smooth muscle alpha-actin; smooth muscle gamma-actin; vascular smooth muscle alpha-actin; VSCM; wu:fa27h01; wu:fb63d03; wu:fb83f06; wu:fd18f05; XELAEV_18045052mg; zeh0631
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA