ATG16L1 Polyclonal Antibody | Invitrogen PA1-18296 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ATG16L1 Polyclonal Antibody

catalog :

PA1-18296

quantity :

100 uL

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, ELISA, immunocytochemistry

citations: 1

Reference
Bah A, Sanicas M, Nigou J, Guilhot C, Astarie Dequeker C, Vergne I. The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages. Cells. 2020;9: pubmed publisher

product information

Product Type :

Antibody

Product Name :

ATG16L1 Polyclonal Antibody

Catalog # :

PA1-18296

Quantity :

100 uL

Price :

US 474.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Rat

Applications :

ELISA: 1:2,000-1:3,000, Immunocytochemistry: 1:100 - 1:3000, Western Blot: 1:100

Species :

Human, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Autophagy related protein 16 L is encoded by the ATG16L gene and is located on chromosome 2 in humans. It is also known as WD30 or IBD10 (Inflammatory Bowel Disease 10). ATG 12 and ATG5 conjugate with each other and undergoes homo oligomerisation with ATG16L to form an 800 kDa complex called the Atg16L complex. This complex facilitates coupling or lipidation of LC3 to phosphatidylethanolamine (PE) and this ubiquitin-like conjugation system is a widely used marker for autophagy. However, the ATG 16L complex along with other ATGs like ATG 18 and ATG 21 prevent the premature cleavage of ATG8-PE by the cysteine protease, Atg4 until the autophagosome is deemed complete.

Immunogen :

Synthetic peptide corresponding to the N-terminal residues of human ATG16-L1.

Format :

Lyophilized

Applications w/Dilutions :

ELISA: 1:2,000-1:3,000, Immunocytochemistry: 1:100 - 1:3000, Western Blot: 1:100

Aliases :

1500009K01Rik; A16L1; APG 16-L1; Apg16l; APG16L beta; APG16L isoforms 1; APG16-like 1; atg16; ATG16 autophagy related 16-like 1; ATG16A; Atg16l; Atg16l1; Atg16L1 gamma; autophagy related 16 like 1; autophagy related 16-like 1; autophagy related 16-like 1 (S. cerevisiae); autophagy-related 16-like 1; autophagy-related 16-like 1 gamma; autophagy-related protein 16-1; hCG_1817841; IBD10; UNQ9393/PRO34307; WD repeat domain 30; Wdr30