DNM1L Polyclonal Antibody | Invitrogen PA1-16987 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DNM1L Polyclonal Antibody

catalog :

PA1-16987

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:1000; fig 4	Hyun H, Ko A, Kang T. Mitochondrial Translocation of High Mobility Group Box 1 Facilitates LIM Kinase 2-Mediated Programmed Necrotic Neuronal Death. Front Cell Neurosci. 2016;10:99 pubmed publisher
	Nguyen T, Gadet R, Lanfranchi M, Lahaye R, Yandiev S, Lohez O, et al. Mitochondrial Bcl-xL promotes brain synaptogenesis by controlling non-lethal caspase activation. iScience. 2023;26:106674 pubmed publisher
	Kim J, Kim T, Kang T. EGCG Attenuates CA1 Neuronal Death by Regulating GPx1, NF-κB S536 Phosphorylation and Mitochondrial Dynamics in the Rat Hippocampus following Status Epilepticus. Antioxidants (Basel). 2023;12: pubmed publisher
	Lee D, Kim T, Park H, Kim J. CDDO-Me Abrogates Aberrant Mitochondrial Elongation in Clasmatodendritic Degeneration by Regulating NF-κB-PDI-Mediated S-Nitrosylation of DRP1. Int J Mol Sci. 2023;24: pubmed publisher
	Mandik F, Kanana Y, Rody J, Misera S, Wilken B, Laabs von Holt B, et al. A new model for fatty acid hydroxylase-associated neurodegeneration reveals mitochondrial and autophagy abnormalities. Front Cell Dev Biol. 2022;10:1000553 pubmed publisher
	Hotta T, McAlear T, Yue Y, Higaki T, Haynes S, Nesvizhskii A, et al. EML2-S constitutes a new class of proteins that recognizes and regulates the dynamics of tyrosinated microtubules. Curr Biol. 2022;32:3898-3910.e14 pubmed publisher
	Lee D, Kim T, Park H, Kim J. CDDO-Me Attenuates Clasmatodendrosis in CA1 Astrocyte by Inhibiting HSP25-AKT Mediated DRP1-S637 Phosphorylation in Chronic Epilepsy Rats. Int J Mol Sci. 2022;23: pubmed publisher
	Monsálves Álvarez M, Morales P, Castro Sepúlveda M, Sepúlveda C, Rodriguez J, Chiong M, et al. β-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle. Nutrients. 2020;12: pubmed publisher
	Kim J, Park H, Choi S, Kong M, Kang T. CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1. Cells. 2019;8: pubmed publisher
	Lee D, Kim J. PDI-mediated S-nitrosylation of DRP1 facilitates DRP1-S616 phosphorylation and mitochondrial fission in CA1 neurons. Cell Death Dis. 2018;9:869 pubmed publisher
	Ko A, Hyun H, Min S, Kim J, Kang T. Endothelin-1 induces LIMK2-mediated programmed necrotic neuronal death independent of NOS activity. Mol Brain. 2015;8:58 pubmed publisher

product information

Product Type :

Antibody

Product Name :

DNM1L Polyclonal Antibody

Catalog # :

PA1-16987

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Fish, Human, Mouse, Non-human primate, Rat

Applications :

Flow Cytometry: 1:1,000, Immunocytochemistry: 1:500, Immunohistochemistry (Paraffin): 2.5 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: 1:500

Species :

Fish, Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

-20 C or -80 C if preferred

Description :

A human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses.

Immunogen :

Synthetic peptide corresponding to residues 500-600 of human DRP1.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:1,000, Immunocytochemistry: 1:500, Immunohistochemistry (Paraffin): 2.5 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: 1:500

Aliases :

6330417M19Rik; AI450666; C-terminal region; Dlp1; dnm1l; Dnm1p/Vps1p-like protein; Dnml1; Dnmlp1; Drp1; DVLP; DYMPLE; dynamin 1 like; dynamin 1-like; dynamin family member proline-rich carboxyl-terminal domain less; Dynamin-1-like protein; Dynamin-1-like protein-like protein; Dynamin-like protein; dynamin-like protein 1; dynamin-like protein 4; Dynamin-like protein IV; dynamin-related protein 1; DYNIV 11; DYNIV-11; EC 3.6.5.5; EGK_03514; EMPF; FLJ41912; HDYNIV; N-terminal region; python; similar to dynamin 1-like; VPS1; zgc:66163

more info or order :

Invitrogen product webpage