This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
KCNK2 Polyclonal Antibody
catalog :
PA1-16981
quantity :
100 uL
price :
US 454.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, bovine
application :
western blot
product information
Product Type :
Antibody
Product Name :
KCNK2 Polyclonal Antibody
Catalog # :
PA1-16981
Quantity :
100 uL
Price :
US 454.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Bovine, Human, Mouse
Applications :
Western Blot: 1:1,000
Species :
Bovine, Human, Mouse
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
TREK-1 is a two-pore-domain background potassium channel expressed throughout the central nervous system. It is opened by polyunsaturated fatty acids and lysophospholipids. As well, it is regulated by various neurotransmitters. It has been shown that alterations in the functioning, regulation, or both of the TREK-1 channel may alter mood. TREK-1 is also activated by volatile anesthetics and has been suggested to be an important target in the action of these drugs. Therefore, this particular K+ channel emerges as a potential innovative target for developing new therapeutic agents for anesthesiology and neurology, such as antidepressants.
Immunogen :
Synthetic peptide within the N-terminal region (residues 1-100) of human TREK 1.
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:1,000
Aliases :
A430027H14Rik; AI848635; arachidonic acid sensitive tandem pore domain potassium channel; EMBL:AAU06141.1, ECO:0000312; Ensembl:ENSRNOP00000003684, ECO:0000312; hTREK-1c; hTREK-1e; ion transport membrane protein; K2p2.1; K2P2.1 potassium channel; KCNK2; kcnk2 {ECO:0000312; Kcnk2 potassium channel; outward rectifying potassium channel protein TREK-1; outward rectifying potassium channel protein TREK-1 {ECO:0000250; Potassium channel subfamily K member 2; potassium channel subfamily K member 2 {ECO:0000250; potassium channel subfamily k member 2 variant 1; potassium channel subfamily k member 2 variant 2; potassium channel, subfamily K, member 2; potassium channel, two pore domain subfamily K, member 2; potassium inwardly-rectifying channel, subfamily K, member 2; potassium two pore domain channel subfamily K member 2; PubMed:16248991}; PubMed:24196565}; RGD:621448}; rTREK1d; Stretch-activated potassium channel TREK-1; stretch-activated potassium channel TREK-1 {ECO:0000303; tandem-pore-domain potassium channel TREK-1; TPKC1; TREK; trek 1; TREK1; TREK-1; TREK-1 K(+) channel subunit; TREK-1 K(+) channel subunit {ECO:0000250; TWIK-related potassium channel 1; two pore domain potassium channel TREK-1; two pore domain potassium channel TREK-1 {ECO:0000303; Two pore potassium channel TPKC1; two pore potassium channel TPKC1 {ECO:0000250; two-pore potassium channel 1; UniProtKB:O95069}
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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