ADFP Polyclonal Antibody | Invitrogen PA1-16972 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ADFP Polyclonal Antibody

catalog :

PA1-16972

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; loading ...; fig 5b	Ogasawara Y, Cheng J, Tatematsu T, Uchida M, Murase O, Yoshikawa S, et al. Long-term autophagy is sustained by activation of CCTβ3 on lipid droplets. Nat Commun. 2020;11:4480 pubmed publisher
	Arbaizar Rovirosa M, Gallizioli M, Lozano J, Sidorova J, Pedragosa J, Figuerola S, et al. Transcriptomics and translatomics identify a robust inflammatory gene signature in brain endothelial cells after ischemic stroke. J Neuroinflammation. 2023;20:207 pubmed publisher
	Arbaizar Rovirosa M, Pedragosa J, Lozano J, Casal C, Pol A, Gallizioli M, et al. Aged lipid-laden microglia display impaired responses to stroke. EMBO Mol Med. 2023;15:e17175 pubmed publisher
	Masetti M, Carriero R, Portale F, Marelli G, Morina N, Pandini M, et al. Lipid-loaded tumor-associated macrophages sustain tumor growth and invasiveness in prostate cancer. J Exp Med. 2022;219: pubmed publisher
	Du Y, Sun D, Li Y. Mex3c mutation affects lactation through impairing milk ejection in female mice. Biosci Rep. 2020;40: pubmed publisher
	Gouveia L, Kraut S, Hadžić S, Vazquéz Liébanas E, Kojonazarov B, Wu C, et al. Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung. Am J Physiol Lung Cell Mol Physiol. 2020;318:L831-L843 pubmed publisher
	Little H, Rodriguez S, Lei X, Tan S, Stewart A, Sahagun A, et al. Myonectin deletion promotes adipose fat storage and reduces liver steatosis. FASEB J. 2019;33:8666-8687 pubmed publisher
	Gouveia L, Betsholtz C, Andrae J. PDGF-A signaling is required for secondary alveolar septation and controls epithelial proliferation in the developing lung. Development. 2018;145: pubmed publisher
	Mulye M, Zapata B, Gilk S. Altering lipid droplet homeostasis affects Coxiella burnetii intracellular growth. PLoS ONE. 2018;13:e0192215 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ADFP Polyclonal Antibody

Catalog # :

PA1-16972

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:200, Western Blot: 2 ug/mL

Species :

Bovine, Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase. ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.

Immunogen :

Synthetic peptide corresponding to the C-terminal region (within residues 350-425) of mouse ADFP.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:200, Western Blot: 2 ug/mL

Aliases :

AA407157; Adfp; Adipophilin; adipose differentiation related protein; adipose differentiation-related protein; ADPH; Adrp; ADRP antibody; MGC10598; perilipin 2; perilipin-2; Plin2

more info or order :

Invitrogen product webpage