product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SOX2 Polyclonal Antibody
catalog :
PA1-16968
quantity :
100 uL
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs, domestic sheep
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 21
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig s4
Nickolls A, Lee M, Espinoza D, Szczot M, Lam R, Wang Q, et al. Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells. Cell Rep. 2020;30:932-946.e7 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 1g
Alonso Barroso E, Brasil S, Briso Montiano Á, Navarrete R, Perez Cerda C, Ugarte M, et al. Generation and characterization of a human iPSC line from a patient with propionic acidemia due to defects in the PCCA gene. Stem Cell Res. 2017;23:173-177 pubmed publisher
  • immunohistochemistry; human; fig 3
Castaño J, Morera C, Sesé B, Boue S, Bonet Costa C, Marti M, et al. SETD7 Regulates the Differentiation of Human Embryonic Stem Cells. PLoS ONE. 2016;11:e0149502 pubmed publisher
Appeltant R, Hermes R, Holtze S, Modina S, Galli C, Bjarkadottir B, et al. The neonatal southern white rhinoceros ovary contains oogonia in germ cell nests. Commun Biol. 2023;6:1049 pubmed publisher
Yang X, Wan R, Liu Z, Feng S, Yang J, Jing N, et al. The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes. elife. 2023;12: pubmed publisher
Ortu xf1 o Costela M, Cerrada V, Moreno Izquierdo A, Garc xed a Consuegra I, Laberthonni xe8 re C, Delourme M, et al. Generation of the First Human In Vitro Model for McArdle Disease Based on iPSC Technology. Int J Mol Sci. 2022;23: pubmed publisher
Hekman K, Koss K, Ivancic D, He C, Wertheim J. Autophagy Enhances Longevity of Induced Pluripotent Stem Cell-Derived Endothelium via mTOR-Independent ULK1 Kinase. Stem Cells Transl Med. 2022;11:1151-1164 pubmed publisher
Cai M, Chai S, Xiong T, Wei J, Mao W, Zhu Y, et al. Aberrant Expression of Circulating MicroRNA Leads to the Dysregulation of Alpha-Synuclein and Other Pathogenic Genes in Parkinson's Disease. Front Cell Dev Biol. 2021;9:695007 pubmed publisher
Shah N, Hallur P, Ganesh R, Sonpatki P, Naik D, Chandrachari K, et al. Gelatin methacrylate hydrogels culture model for glioblastoma cells enriches for mesenchymal-like state and models interactions with immune cells. Sci Rep. 2021;11:17727 pubmed publisher
Fütterer A, Talavera Gutiérrez A, Pons T, de Celis J, Gutierrez J, Domínguez Plaza V, et al. Impaired stem cell differentiation and somatic cell reprogramming in DIDO3 mutants with altered RNA processing and increased R-loop levels. Cell Death Dis. 2021;12:637 pubmed publisher
Raj N, McEachin Z, Harousseau W, Zhou Y, Zhang F, Merritt Garza M, et al. Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis. Cell Rep. 2021;35:108991 pubmed publisher
Kruminis Kaszkiel E, Osowski A, Bejer Olenska E, Dziekoński M, Wojtkiewicz J. Differentiation of Human Mesenchymal Stem Cells from Wharton's Jelly Towards Neural Stem Cells Using A Feasible and Repeatable Protocol. Cells. 2020;9: pubmed publisher
Elfar M, Amleh A. miR-590-3p and Its Downstream Target Genes in HCC Cell Lines. Anal Cell Pathol (Amst). 2019;2019:3234812 pubmed publisher
Gupta M, Polisetty R, Sharma R, Ganesh R, Gowda H, Purohit A, et al. Altered transcriptional regulatory proteins in glioblastoma and YBX1 as a potential regulator of tumor invasion. Sci Rep. 2019;9:10986 pubmed publisher
López Márquez A, Alonso Barroso E, Cerro Tello G, Bravo Alonso I, Arribas Carreira L, Briso Montiano Á, et al. Generation and characterization of a human iPSC line (UAMi004-A) from a patient with propionic acidemia due to defects in the PCCB gene. Stem Cell Res. 2019;38:101469 pubmed publisher
Arellano Viera E, Zabaleta L, Castaño J, Azkona G, Carvajal Vergara X, Giorgetti A. Generation of two transgene-free human iPSC lines from CD133+ cord blood cells. Stem Cell Res. 2019;36:101410 pubmed publisher
Haghighi F, Dahlmann J, Nakhaei Rad S, Lang A, Kutschka I, Zenker M, et al. bFGF-mediated pluripotency maintenance in human induced pluripotent stem cells is associated with NRAS-MAPK signaling. Cell Commun Signal. 2018;16:96 pubmed publisher
Glen C, McDevitt T, Kemp M. Dynamic intercellular transport modulates the spatial patterning of differentiation during early neural commitment. Nat Commun. 2018;9:4111 pubmed publisher
Richard E, Brasil S, Briso Montiano Á, Alonso Barroso E, Gallardo M, Merinero B, et al. Generation and characterization of two human iPSC lines from patients with methylmalonic acidemia cblB type. Stem Cell Res. 2018;29:143-147 pubmed publisher
Ortuño Costela M, Moreno Izquierdo A, Garesse R, Gallardo M. Generation of a human iPSC line, IISHDOi002-A, with a 46, XY/47, XYY mosaicism and belonging to an African mitochondrial haplogroup. Stem Cell Res. 2018;28:131-135 pubmed publisher
Ventura Ferreira M, Bienert M, Muller K, Rath B, Goecke T, Opländer C, et al. Comprehensive characterization of chorionic villi-derived mesenchymal stromal cells from human placenta. Stem Cell Res Ther. 2018;9:28 pubmed publisher
product information
Product Type :
Antibody
Product Name :
SOX2 Polyclonal Antibody
Catalog # :
PA1-16968
Quantity :
100 uL
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Canine, Human, Mouse, Ovine, Rat
Applications :
Flow Cytometry: 1:100, Immunocytochemistry: 1:50-1:250, Immunohistochemistry (Paraffin): 1:125-1:250, Western Blot: 0.5 ug/mL
Species :
Canine, Human, Mouse, Ovine, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
Immunogen :
Synthetic peptide made to the N-terminal region of human SOX2 protein (within residues 1-100). [Swiss-Prot# P48431]
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:100, Immunocytochemistry: 1:50-1:250, Immunohistochemistry (Paraffin): 1:125-1:250, Western Blot: 0.5 ug/mL
Aliases :
ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA