SLC7A11 Polyclonal Antibody | Invitrogen PA1-16893 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SLC7A11 Polyclonal Antibody

catalog :

PA1-16893

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, western blot knockout validation

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; loading ...; fig 7e immunohistochemistry; human; fig 7f western blot knockout validation; mouse; loading ...; fig 5h immunohistochemistry; mouse; loading ...; fig 1e	Choi W, Kim H, Kim M, Cinar R, Yi H, Eun H, et al. Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis. Cell Metab. 2019;30:877-889.e7 pubmed publisher
western blot; mouse; fig 2	Van Liefferinge J, Bentea E, Demuyser T, Albertini G, Follin Arbelet V, Holmseth S, et al. Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed. J Comp Neurol. 2016;524:1015-32 pubmed publisher
	Liu Y, Wu K, Fu Y, Li W, Zhao X. Slc7a11 stimulates glutathione synthesis to preserve fatty acid metabolism in primary hepatocytes. Redox Rep. 2023;28:2260646 pubmed publisher
	Sun M, Liu M, Li Q, Zhang X, Liu S, Yang H, et al. Cottonseed oil alleviates ischemic stroke injury by inhibiting ferroptosis. Brain Behav. 2023;13:e3179 pubmed publisher
	Tang Y, Liu C, Zhu T, Chen H, Sun Y, Zhang X, et al. Transcriptome Profiles of IncRNA and mRNA Highlight the Role of Ferroptosis in Chronic Neuropathic Pain With Memory Impairment. Front Cell Dev Biol. 2022;10:843297 pubmed publisher
	Koch K, Hartmann R, Suwala A, Rios D, Kamp M, Sabel M, et al. Overexpression of Cystine/Glutamate Antiporter xCT Correlates with Nutrient Flexibility and ZEB1 Expression in Highly Clonogenic Glioblastoma Stem-like Cells (GSCs). Cancers (Basel). 2021;13: pubmed publisher
	Zhu Y, Zhang C, Huang M, Lin J, Fan X, Ni T. TRIM26 Induces Ferroptosis to Inhibit Hepatic Stellate Cell Activation and Mitigate Liver Fibrosis Through Mediating SLC7A11 Ubiquitination. Front Cell Dev Biol. 2021;9:644901 pubmed publisher
	Yao C, Wang R, Wang Y, Kung C, Weber J, Patti G. Mitochondrial fusion supports increased oxidative phosphorylation during cell proliferation. elife. 2019;8: pubmed publisher
	Shin S, Jeong B, Wall B, Li J, Shan N, Wen Y, et al. Participation of xCT in melanoma cell proliferation in vitro and tumorigenesis in vivo. Oncogenesis. 2018;7:86 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SLC7A11 Polyclonal Antibody

Catalog # :

PA1-16893

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 2-3 ug/mL, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

SLC7A11 (also known as XCT) is a member of a hetromeric, sodium-independent, anionic amino acid transport system. It is highly specific for cysteine and glutamate. SLC7A11 is a mediator of Kaposi sarcoma-associated herpes virus fusion and entry into cells. Increased expression of this protein in primary gliomas is associated with neuronal cell death.

Immunogen :

Synthetic peptide between amino acid 1-50 of the human XCT protein.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 2-3 ug/mL, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 1:1,000

Aliases :

9930009M05Rik; AI451155; Amino acid transport system xc-; calcium channel blocker resistance protein CCBR1; CCBR1; cysteine/glutamate transporter; cystine/glutamate transporter; SLC7A11; sodium independent anionic amino acid transport system; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7 (cationic amino acid transporter, y+ system), member 11; solute carrier family 7 member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; sut; xCT

more info or order :

Invitrogen product webpage