This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NPC1L1 Polyclonal Antibody
catalog :
PA1-16800
quantity :
100 uL
price :
US 454.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, pigs
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 4
Reference
Elste J, Cast N, Udawatte S, Adhikari K, Payen S, Verma S, et al. Co-Expression of Niemann-Pick Type C1-Like1 (NPC1L1) with ACE2 Receptor Synergistically Enhances SARS-CoV-2 Entry and Fusion. Biomedicines. 2024;12: pubmed publisher
Shen W, Shao W, Wang Q, Wang B, Zhao G, Gu A, et al. Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice. J Biomed Sci. 2023;30:44 pubmed publisher
Sun Y, Tang Y, Hou X, Wang H, Huang L, Wen J, et al. Novel Lactobacillus reuteri HI120 Affects Lipid Metabolism in C57BL/6 Obese Mice. Front Vet Sci. 2020;7:560241 pubmed publisher
Hiebl V, Schachner D, Ladurner A, Heiss E, Stangl H, Dirsch V. Caco-2 Cells for Measuring Intestinal Cholesterol Transport - Possibilities and Limitations. Biol Proced Online. 2020;22:7 pubmed publisher
product information
Product Type :
Antibody
Product Name :
NPC1L1 Polyclonal Antibody
Catalog # :
PA1-16800
Quantity :
100 uL
Price :
US 454.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Porcine, Rat
Applications :
ELISA: Assay-Dependent, Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Paraffin): 1:100-1:250, Immunomicroscopy: Assay-Dependent, Western Blot: 2 ug/mL
Species :
Human, Mouse, Porcine, Rat
Isotype :
IgG
Storage :
4 C, do not freeze
Description :
Dietary consumption and intestinal cholesterol absorption contribute to plasma cholesterol levels, which factor into the risk of coronary heart disease. Niemann-Pick type C1 Like 1 protein (NPC1L1 or NPC3) is enriched in the small intestine and is found in the brush border membrane of enterocytes. It plays a critical role in absorption of intestinal cholesterol.
Immunogen :
A synthetic peptide made to an internal region of rat NPC1L1(between residues 1000-1100).
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-Dependent, Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Paraffin): 1:100-1:250, Immunomicroscopy: Assay-Dependent, Western Blot: 2 ug/mL
Aliases :
9130221N23Rik; BC 400-127; Gm243; Niemann-Pick C1-like protein 1; Niemann-Pick C3; Niemann-Pick disease, type C1; Niemann-Pick disease, type C1-like 1; NPC1 (Niemann-Pick disease, type C1, gene)-like 1; NPC1 like 1; NPC1 like intracellular cholesterol transporter 1; NPC11L1; NPC1L1; NPC1-like 1; NPC1-like intracellular cholesterol transporter 1; NPC3
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA