ABCA1 Polyclonal Antibody | Invitrogen PA1-16789 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ABCA1 Polyclonal Antibody

catalog :

PA1-16789

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Chinese hamsters, human, mouse, rat, dogs, chicken, pigs , domestic rabbit

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500; fig 2	Perez J, Dansou B, HervÃ© R, Levi C, Tamouza H, Vandermeersch S, et al. Calpains Released by T Lymphocytes Cleave TLR2 To Control IL-17 Expression. J Immunol. 2016;196:168-81 pubmed publisher
	Paterson H, Yu S, Artigas N, Prado M, Haberman N, Wang Y, et al. Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice. Nat Metab. 2022;4:1812-1829 pubmed publisher
	Godwin C, Anders J, Cheng L, Elwood B, Kardon R, Gramlich O. Targeting Cholesterol Homeostasis Improves Recovery in Experimental Optic Neuritis. Biomolecules. 2022;12: pubmed publisher
	Taiarol L, Bigogno C, Sesana S, Kravicz M, Viale F, Pozzi E, et al. Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and Pharmacokinetics. Cancers (Basel). 2022;14: pubmed publisher
	Sun M, Beier F. Liver X Receptor activation regulates genes involved in lipid homeostasis in developing chondrocytes. Osteoarthr Cartil Open. 2020;2:100030 pubmed publisher
	Wang G, Chen J, Deng W, Ren K, Yin S, Yu X. CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRα pathway. Cell Death Dis. 2021;12:254 pubmed publisher
	Lee Y, Joo H, Lee E, Cho H, Choi S, Kim C, et al. ATP Binding Cassette Transporter A1 is Involved in Extracellular Secretion of Acetylated APE1/Ref-1. Int J Mol Sci. 2019;20: pubmed publisher
	Zhou Y, Miles J, Tavori H, Lin M, Khoshbouei H, Borchelt D, et al. PMP22 regulates cholesterol trafficking and ABCA1-mediated cholesterol efflux. J Neurosci. 2019;: pubmed publisher
	Kim H, Baek W, Han M, Jung J, Suh C. The Liver X Receptor Is Upregulated in Monocyte-Derived Macrophages and Modulates Inflammatory Cytokines Based on LXRα Polymorphism. Mediators Inflamm. 2019;2019:6217548 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ABCA1 Polyclonal Antibody

Catalog # :

PA1-16789

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Canine, Chicken, Hamster, Human, Mouse, Mustelid, Non-human primate, Porcine, Rabbit, Rat

Applications :

ChIP Assay: Assay-Dependent, ELISA: Assay-Dependent, Flow Cytometry: 1:400, Gel Shift: Assay-Dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: 1:10-1:500, Neutralization: Assay-Dependent, Western Blot: 1:500-1:1,000

Species :

Canine, Chicken, Hamster, Human, Mouse, Mustelid, Non-human primate, Porcine, Rabbit, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.

Immunogen :

Partial peptide sequence corresponding to a sequence between residues 1100-1300 of human ABCA1.

Format :

Liquid

Applications w/Dilutions :

Aliases :

ABC 1; ABC 1 antibody; ABC Transporter 1; Abc1; ABC-1; ABC1 antibody; Abca1; ATP binding cassette subfamily A member 1; ATP-binding cassette 1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ATP-binding cassette transporter A1; ATP-binding cassette, subfamily A (ABC1), member 1; ATP-binding cassette, sub-family A (ABC1), member 1; ATP-binding cassette, sub-family A member 1; CERP; CERP antibody; Cholesterol efflux regulatory protein; HDLDT1; membrane-bound; phospholipid-transporting ATPase ABCA1; phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; TGD

more info or order :

Invitrogen product webpage