This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SR-BI Polyclonal Antibody
catalog :
PA1-16788
quantity :
100 uL
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
Chinese hamsters, human, mouse, rat, pigs , domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay
citations: 1
Reference
Fuentes M, Santander N, Cortés V. Insulin increases cholesterol uptake, lipid droplet content, and apolipoprotein B secretion in CaCo-2 cells by upregulating SR-BI via a PI3K, AKT, and mTOR-dependent pathway. J Cell Biochem. 2018;: pubmed publisher
product information
Product Type :
Antibody
Product Name :
SR-BI Polyclonal Antibody
Catalog # :
PA1-16788
Quantity :
100 uL
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Hamster, Human, Mink, Mouse, Non-human primate, Porcine, Rabbit, Rat
Applications :
Flow Cytometry: 1:10-1:1,000, Immunocytochemistry: 1:50-1:1,000, Immunohistochemistry (Frozen): 2.5-5 ug/mL, Immunohistochemistry (Paraffin): 2.5-5 ug/mL, Immunoprecipitation: 1:10-1:500, Neutralization: Assay-Dependent, Proximity Ligation Assay (PLA): Assay-Dependent, Western Blot: 1:1,000-1:5,000
Species :
Hamster, Human, Mink, Mouse, Non-human primate, Porcine, Rabbit, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
Immunogen :
Synthetic peptide corresponding to a region within the residues 450-509 of mouse Scavenger Receptor-BI.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:10-1:1,000, Immunocytochemistry: 1:50-1:1,000, Immunohistochemistry (Frozen): 2.5-5 ug/mL, Immunohistochemistry (Paraffin): 2.5-5 ug/mL, Immunoprecipitation: 1:10-1:500, Neutralization: Assay-Dependent, Proximity Ligation Assay (PLA): Assay-Dependent, Western Blot: 1:1,000-1:5,000
Aliases :
AI120173; CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen (collagen type I receptor, thrombospondin receptor-like 1); CD36 antigen-like 1; Cd36l1; CD36-related class B scavenger receptor haSR-BI; CLA1; Cla-1; Collagen type I receptor, thrombospondin receptor-like 1; D5Ertd460e; haSR-bI; HDL QTL 1; Hdlq1; HDLQTL6; high density lipoprotein receptor; Hlb398; mSR-BI; Scarb1; scavanger receptor class B type 1; scavenger receptor b1; scavenger receptor class B member 1; scavenger receptor class B type I; scavenger receptor class B type II; scavenger receptor class B type III; scavenger receptor class B, member 1; scavenger receptor class B1; SRB1; SR-B1; SRBI; SR-BI; SR-BII
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA