Vimentin Polyclonal Antibody | Invitrogen PA1-16759 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Vimentin Polyclonal Antibody

catalog :

PA1-16759

quantity :

100 µL

price :

US 510.00

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, chicken, bovine, pigs , domestic horse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:2000; loading ...; fig 2a	Rivera Serrano E, Sherry B. NF-?B activation is cell type-specific in the heart. Virology. 2017;502:133-143 pubmed publisher
	Stern S, Hilton B, Burnside E, Dupraz S, Handley E, Gonyer J, et al. RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury. Neuron. 2021;109:3436-3455.e9 pubmed publisher
	Andreichenko I, Tsitrina A, Fokin A, Gabdulkhakova A, Maltsev D, Perelman G, et al. 4-methylumbelliferone Prevents Liver Fibrosis by Affecting Hyaluronan Deposition, FSTL1 Expression and Cell Localization. Int J Mol Sci. 2019;20: pubmed publisher
	Libanje F, Raingeaud J, Luan R, Thomas Z, Zajac O, Veiga J, et al. ROCK2 inhibition triggers the collective invasion of colorectal adenocarcinomas. EMBO J. 2019;38:e99299 pubmed publisher
	Watson S, Duff J, Bardi I, Zabielska M, Atanur S, Jabbour R, et al. Biomimetic electromechanical stimulation to maintain adult myocardial slices in vitro. Nat Commun. 2019;10:2168 pubmed publisher
	Di Spiezio A, Sandin E, Dore R, Müller Fielitz H, Storck S, Bernau M, et al. The LepR-mediated leptin transport across brain barriers controls food reward. Mol Metab. 2018;8:13-22 pubmed publisher
	Müller Fielitz H, Stahr M, Bernau M, Richter M, Abele S, Krajka V, et al. Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis. Nat Commun. 2017;8:484 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Vimentin Polyclonal Antibody

Catalog # :

PA1-16759

Quantity :

100 µL

Price :

US 510.00

Clonality :

Polyclonal

Purity :

IgY fraction

Host :

Chicken

Reactivity :

Bovine, Canine, Chicken, Equine, Human, Mouse, Porcine, Rat

Applications :

Immunocytochemistry: 1:200-1:5000, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:10,000-1:20,000

Species :

Bovine, Canine, Chicken, Equine, Human, Mouse, Porcine, Rat

Isotype :

IgY

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.

Immunogen :

The immunogen used to generate our antibody was recombinant vimentin purified from E. coli.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:200-1:5000, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:10,000-1:20,000

Aliases :

cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus

more info or order :

Invitrogen product webpage