GADD34 Polyclonal Antibody | Invitrogen PA1-139 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GADD34 Polyclonal Antibody

catalog :

PA1-139

quantity :

100 ug

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 7

Reference
Stein D, Slobodnik Z, Tam B, Einav M, Akabayov B, Berstein S, et al. 4-phenylbutyric acid-Identity crisis; can it act as a translation inhibitor?. Aging Cell. 2022;21:e13738 pubmed publisher
Alfred N, Qian B, Qin X, Yin X, Prajapati M, Dou Y, et al. Inhibition of eIF2α Phosphorylation by Peste des Petits Ruminant Virus Phosphoprotein Facilitates Viral Replication. Front Vet Sci. 2021;8:645571 pubmed publisher
Attwood K, Robichaud A, Westhaver L, Castle E, Brandman D, Balgi A, et al. Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells. Cell Death Dis. 2020;11:989 pubmed publisher
Gambardella G, Staiano L, Moretti M, De Cegli R, Fagnocchi L, Di Tullio G, et al. GADD34 is a modulator of autophagy during starvation. Sci Adv. 2020;6: pubmed publisher
Mytych J, Sołek P, Będzińska A, Rusinek K, Warzybok A, Tabęcka Łonczyńska A, et al. Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes. Cells. 2020;9: pubmed publisher
Krishnamoorthy G, Davidson N, Leach S, Zhao Z, Lowe S, Lee G, et al. EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC. Cancer Discov. 2019;9:264-281 pubmed publisher
Poli M, Ebstein F, Nicholas S, de Guzman M, Forbes L, Chinn I, et al. Heterozygous Truncating Variants in POMP Escape Nonsense-Mediated Decay and Cause a Unique Immune Dysregulatory Syndrome. Am J Hum Genet. 2018;102:1126-1142 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GADD34 Polyclonal Antibody

Catalog # :

PA1-139

Quantity :

100 ug

Price :

US 451.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:50-1:100, Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

Immunogen :

A synthetic peptide corresponding to amino acids C R(595) I T Q A Q E E L S P C L T P A A R(612) from human GADD34

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:50-1:100, Western Blot: 1:1,000

Aliases :

9630030H21; Gadd34; growth arrest and DNA damage-inducible protein GADD34; growth arrest and DNA-damage-inducible 34; Myd116; myeloid differentiation primary response gene 116; myeloid differentiation primary response protein MyD116; Myeloid differentiation primary response protein MyD116 homolog; Peg3; PEG-3; PPP1R15A; PR15A; Progression elevated gene 3 protein; protein phosphatase 1 regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A; protein phosphatase 1, regulatory subunit 15A; RGD1624209