KV2.2 (KCNB2) Polyclonal Antibody | Invitrogen PA1-12750 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KV2.2 (KCNB2) Polyclonal Antibody

catalog :

PA1-12750

quantity :

10Miniblots

price :

381 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat, common platanna

application :

western blot, immunohistochemistry

product information

Product Type :

Antibody

Product Name :

KV2.2 (KCNB2) Polyclonal Antibody

Catalog # :

PA1-12750

Quantity :

10Miniblots

Price :

381 USD

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Mouse, Rat, Xenopus laevis

Applications :

Immunohistochemistry: Assay Dependent, Western Blot: Assay Dependent

Species :

Mouse, Rat, Xenopus laevis

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Kcnb2 (Kv2.2) encodes a Voltage-gated K+ channel which are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variation in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK) channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety on non-neuronal cell types including pancreatic islet , alveolar cells and cardiac myocytes. Kv2.1 and Kcnb2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells. Functionally, Kcnb2 mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient. Diseases associated with KCNB2 include Brugada Syndrome.

Immunogen :

Synthetic peptide from rat voltage gated potassium channel, Kv2.2-subunit conjugated to KLH

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: Assay Dependent, Western Blot: Assay Dependent

Aliases :

Kv2.2