SH2D1A Polyclonal Antibody | Invitrogen PA1-12645 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SH2D1A Polyclonal Antibody

catalog :

PA1-12645

quantity :

100 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

SH2D1A Polyclonal Antibody

Catalog # :

PA1-12645

Quantity :

100 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Rabbit

Reactivity :

Human

Applications :

Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Full-length recombinant SAP protein.

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

DSHP; Duncan disease homolog; Duncan disease SH2-protein; Duncan's disease; EBVS; FLJ18687; FLJ92177; Gm686; HGNC:10820; IMD5; LYP; MTCP1; RGD1562408; RP5-1052M9.3; SAP; SAP/SH2D1A; SH2 domain containing 1A; SH2 domain protein 1A; SH2 domain-containing protein 1A; SH2D1A; signaling lymphocyte activation molecule-associated protein; signaling lymphocytic activation molecule-associated protein; SLAM associated protein/SH2 domain protein 1A; SLAM-associated protein; SLAM-associated protein isoform SAP-2; T cell signal transduction molecule SAP; T-cell signal transduction molecule SAP; Xlp; XLPD; XLPD1