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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
GnRH1 Polyclonal Antibody
catalog :
PA1-121
quantity :
100 µg
price :
US 430.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse, bovine
application :
immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 1f
Hoffmann H, Larder R, Lee J, Hu R, Trang C, Devries B, et al. Differential CRE Expression in Lhrh-cre and GnRH-cre Alleles and the Impact on Fertility in Otx2-Flox Mice. Neuroendocrinology. 2019;108:328-342 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 3b
Cheung L, Okano H, Camper S. Sox21 deletion in mice causes postnatal growth deficiency without physiological disruption of hypothalamic-pituitary endocrine axes. Mol Cell Endocrinol. 2017;439:213-223 pubmed publisher
  • immunohistochemistry - free floating section; bovine; 1:10,000; fig 2
Tanco V, Whitlock B, Jones M, Wilborn R, Brandebourg T, Foradori C. Distribution and regulation of gonadotropin-releasing hormone, kisspeptin, RF-amide related peptide-3, and dynorphin in the bovine hypothalamus. Peerj. 2016;4:e1833 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 1
Hoffmann H, Trang C, Gong P, Kimura I, Pandolfi E, Mellon P. Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility. J Neurosci. 2016;36:3506-18 pubmed publisher
Wang H, Parra M, Conboy J, Hillyer C, Mohandas N, An X. Selective effects of protein 4.1N deficiency on neuroendocrine and reproductive systems. Sci Rep. 2020;10:16947 pubmed publisher
Pandolfi E, Breuer J, Nguyen Huu V, Talluri T, Nguyen D, Lee J, et al. The Homeodomain Transcription Factors Vax1 and Six6 Are Required for SCN Development and Function. Mol Neurobiol. 2020;57:1217-1232 pubmed publisher
Lainez N, Jonak C, Nair M, Ethell I, Wilson E, Carson M, et al. Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice. Front Immunol. 2018;9:1992 pubmed publisher
Kumar D, Periasamy V, Freese M, Voigt A, Boehm U. In Utero Development of Kisspeptin/GnRH Neural Circuitry in Male Mice. Endocrinology. 2015;156:3084-90 pubmed publisher
Li R, Diao H, Zhao F, Xiao S, El Zowalaty A, Dudley E, et al. Olfactomedin 1 Deficiency Leads to Defective Olfaction and Impaired Female Fertility. Endocrinology. 2015;156:3344-57 pubmed publisher
Xie C, Jonak C, Kauffman A, Coss D. Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice. Mol Cell Endocrinol. 2015;411:223-31 pubmed publisher
Cholanian M, Krajewski Hall S, McMullen N, Rance N. Chronic oestradiol reduces the dendritic spine density of KNDy (kisspeptin/neurokinin B/dynorphin) neurones in the arcuate nucleus of ovariectomised Tac2-enhanced green fluorescent protein transgenic mice. J Neuroendocrinol. 2015;27:253-63 pubmed publisher
Wen S, Götze I, Mai O, Schauer C, Leinders Zufall T, Boehm U. Genetic identification of GnRH receptor neurons: a new model for studying neural circuits underlying reproductive physiology in the mouse brain. Endocrinology. 2011;152:1515-26 pubmed publisher
image
image 1 :
Invitrogen PA1-121 image 1
Immunolocalization of GnRH in mouse embryo brain using GnRH Polyclonal Antibody (Product #PA1-121).
product information
Product Type :
Antibody
Product Name :
GnRH1 Polyclonal Antibody
Catalog # :
PA1-121
Quantity :
100 µg
Price :
US 430.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Amphibian, Mouse
Applications :
Immunohistochemistry (Paraffin): 1:200-1:1,000
Species :
Amphibian, Mouse
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
The Luteinizing Hormone Releasing Hormone (LH-RH) is produced in the hypothalamus and influences the release of Luteinizing Hormone in the pituitary gland. LH-RH is also known as Gonadotropin-releasing hormone (Gn-RH).
Immunogen :
Synthetic peptide corresponding to residues pyroE(22) H W S Y G L R P G-NH2(32) of mouse GnRH.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:200-1:1,000
Aliases :
Gnrh; Gnrh1; Gnrh2; Gnrha; GnRH-associated peptide 1; GnRH-associated peptide I; GnRH-I; Gonadoliberin I; Gonadoliberin-1; Gonadorelin; gonadotropin releasing hormone 1; gonadotropin releasing hormone 2; gonadotropin-releasing hormone 1 (luteinizing-releasing hormone); gonadotropin-releasing hormone 1 variant A; gonadotropin-releasing hormone 1 variant B; Gonadotropin-releasing hormone I; GRH; hpg; hypogonadal; leuteinizing-releasing hormone; LHRH; LH-RH I; Lhrh1; LNRH; Luliberin I; luteinizing hormone releasing hormone; luteinizing hormone-releasing hormone; luteinizing hormone-releasing hormone I; Lutropin; Progonadoliberin I; progonadoliberin-1; prolactin release-inhibiting factor; Prolactin release-inhibiting factor 1; Prolactin release-inhibiting factor I; Rgnrhg1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA