This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
cAMP Polyclonal Antibody
catalog :
PA1-10840
quantity :
200 uL
price :
US 522.00
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
product information
Product Type :
Antibody
Product Name :
cAMP Polyclonal Antibody
Catalog # :
PA1-10840
Quantity :
200 uL
Price :
US 522.00
Clonality :
Polyclonal
Host :
Sheep
Reactivity :
Chemical
Applications :
ELISA: Assay-dependent
Species :
Chemical
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Cyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery.
Immunogen :
Succinylated cAMP, conjugated to BSA.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent
Aliases :
18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; CAMP; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; Cramp; Cyclic AMP; FALL39; FALL-39; FALL-39 peptide antibiotic; HSD26; LL37; MCLP
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA