product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
GLUT4 Polyclonal Antibody
catalog :
PA1-1065
quantity :
100 µg
price :
US 450.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot
more info or order :
citations: 39
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3
Brocherie F, Millet G, D Hulst G, Van Thienen R, Deldicque L, Girard O. Repeated maximal-intensity hypoxic exercise superimposed to hypoxic residence boosts skeletal muscle transcriptional responses in elite team-sport athletes. Acta Physiol (Oxf). 2018;222: pubmed publisher
  • western blot; human; loading ...; fig 3b
Dandanell S, Skovborg C, Præst C, Kristensen K, Nielsen M, Lionett S, et al. Maintaining a clinical weight loss after intensive lifestyle intervention is the key to cardiometabolic health. Obes Res Clin Pract. 2017;11:489-498 pubmed publisher
  • western blot; human; fig 3
Hansen N, Hjort L, Broholm C, Gillberg L, Schrölkamp M, Schultz H, et al. Metabolic and Transcriptional Changes in Cultured Muscle Stem Cells from Low Birth Weight Subjects. J Clin Endocrinol Metab. 2016;101:2254-64 pubmed publisher
  • western blot; human; fig 3
Andersen T, Schmidt J, Pedersen M, Krustrup P, Bangsbo J. The Effects of 52 Weeks of Soccer or Resistance Training on Body Composition and Muscle Function in +65-Year-Old Healthy Males--A Randomized Controlled Trial. PLoS ONE. 2016;11:e0148236 pubmed publisher
  • western blot; human; fig 3
Hansen M, Lund M, Jørgensen A, Palsøe M, van Hall G, Helge J, et al. The effects of diet- and RYGB-induced weight loss on insulin sensitivity in obese patients with and without type 2 diabetes. Acta Diabetol. 2016;53:423-32 pubmed publisher
  • western blot; human; loading ...; fig 3c
Vigelso A, Prats C, Ploug T, Dela F, Helge J. Higher muscle content of perilipin 5 and endothelial lipase protein in trained than untrained middle-aged men. Physiol Res. 2016;65:293-302 pubmed
Livingstone R, Bryant N, Boyle J, Petrie J, Gould G. Diabetes is accompanied by changes in the levels of proteins involved in endosomal GLUT4 trafficking in obese human skeletal muscle. Endocrinol Diabetes Metab. 2022;5:e361 pubmed publisher
Jessen S, Baasch Skytte T, Onslev J, Eibye K, Backer V, Bangsbo J, et al. Muscle hypertrophic effect of inhaled beta2 -agonist is associated with augmented insulin-stimulated whole-body glucose disposal in young men. J Physiol. 2022;600:2345-2357 pubmed publisher
Bruhn L, Kj xf8 bsted R, Quist J, Gram A, Rosenkilde M, Faerch K, et al. Effect of exercise training on skeletal muscle protein expression in relation to insulin sensitivity: Per-protocol analysis of a randomized controlled trial (GO-ACTIWE). Physiol Rep. 2021;9:e14850 pubmed publisher
Gonzalez Franquesa A, Stocks B, Chubanava S, Hattel H, Moreno Justicia R, Peijs L, et al. Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity. Cell Rep. 2021;35:109180 pubmed publisher
Liśkiewicz A, Marczak Ł, Bogus K, Liśkiewicz D, Przybyła M, Lewin Kowalik J. Proteomic and Structural Manifestations of Cardiomyopathy in Rat Models of Obesity and Weight Loss. Front Endocrinol (Lausanne). 2021;12:568197 pubmed publisher
Mandrup C, Roland C, Egelund J, Nyberg M, Enevoldsen L, Kjaer A, et al. Effects of High-Intensity Exercise Training on Adipose Tissue Mass, Glucose Uptake and Protein Content in Pre- and Post-menopausal Women. Front Sports Act Living. 2020;2:60 pubmed publisher
Møller L, Jaurji M, Kjøbsted R, Joseph G, Madsen A, Knudsen J, et al. Insulin-stimulated glucose uptake partly relies on p21-activated kinase (PAK)2, but not PAK1, in mouse skeletal muscle. J Physiol. 2020;598:5351-5377 pubmed publisher
Møller L, Nielsen I, Knudsen J, Andersen N, Jensen T, Sylow L, et al. The p21-activated kinase 2 (PAK2), but not PAK1, regulates contraction-stimulated skeletal muscle glucose transport. Physiol Rep. 2020;8:e14460 pubmed publisher
Raun S, Henríquez Olguín C, Karavaeva I, Ali M, Møller L, Kot W, et al. Housing temperature influences exercise training adaptations in mice. Nat Commun. 2020;11:1560 pubmed publisher
Ren X, Xu H, Barker R, Lamb G, Murphy R. Elevated MMP2 abundance and activity in mdx mice are alleviated by prenatal taurine supplementation. Am J Physiol Cell Physiol. 2020;318:C1083-C1091 pubmed publisher
Jall S, De Angelis M, Lundsgaard A, Fritzen A, Nicolaisen T, Klein A, et al. Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity. Diabetologia. 2020;63:1236-1247 pubmed publisher
Sabaratnam R, Pedersen A, Eskildsen T, Kristensen J, Wojtaszewski J, H xf8 jlund K. Exercise Induction of Key Transcriptional Regulators of Metabolic Adaptation in Muscle Is Preserved in Type 2 Diabetes. J Clin Endocrinol Metab. 2019;104:4909-4920 pubmed publisher
Søgaard D, Baranowski M, Larsen S, Taulo Lund M, Munk Scheuer C, Vestergaard Abildskov C, et al. Muscle-Saturated Bioactive Lipids Are Increased with Aging and Influenced by High-Intensity Interval Training. Int J Mol Sci. 2019;20: pubmed publisher
Dalbram E, Basse A, Zierath J, Treebak J. Voluntary wheel running in the late dark phase ameliorates diet-induced obesity in mice without altering insulin action. J Appl Physiol (1985). 2019;126:993-1005 pubmed publisher
Dela F, Ingersen A, Andersen N, Nielsen M, Petersen H, Hansen C, et al. Effects of one-legged high-intensity interval training on insulin-mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes. Acta Physiol (Oxf). 2019;226:e13245 pubmed publisher
Kjeld T, Stride N, Gudiksen A, Hansen E, Arendrup H, Horstmann P, et al. Oxygen conserving mitochondrial adaptations in the skeletal muscles of breath hold divers. PLoS ONE. 2018;13:e0201401 pubmed publisher
Basse A, Dalbram E, Larsson L, Gerhart Hines Z, Zierath J, Treebak J. Skeletal Muscle Insulin Sensitivity Show Circadian Rhythmicity Which Is Independent of Exercise Training Status. Front Physiol. 2018;9:1198 pubmed publisher
Raun S, Ali M, Kjøbsted R, Møller L, Federspiel M, Richter E, et al. Rac1 muscle knockout exacerbates the detrimental effect of high-fat diet on insulin-stimulated muscle glucose uptake independently of Akt. J Physiol. 2018;596:2283-2299 pubmed publisher
Jørgensen N, Wojtaszewski J, Kjøbsted R. Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle. Int J Mol Sci. 2018;19: pubmed publisher
Shi H, Munk A, Nielsen T, Daughtry M, Larsson L, Li S, et al. Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity. Mol Metab. 2018;11:160-177 pubmed publisher
Barker R, Frankish B, Xu H, Murphy R. Elevated GLUT4 and glycogenin protein abundance correspond to increased glycogen content in the soleus muscle of mdx mice with no benefit associated with taurine supplementation. Physiol Rep. 2018;6: pubmed publisher
Breuer T, Bleilevens C, Rossaint R, Marx G, Gehrenkemper J, Dierksen H, et al. Dexmedetomidine Impairs Diaphragm Function and Increases Oxidative Stress but Does Not Aggravate Diaphragmatic Atrophy in Mechanically Ventilated Rats. Anesthesiology. 2018;128:784-795 pubmed publisher
Fransson D, Nielsen T, Olsson K, Christensson T, Bradley P, Fatouros I, et al. Skeletal muscle and performance adaptations to high-intensity training in elite male soccer players: speed endurance runs versus small-sided game training. Eur J Appl Physiol. 2018;118:111-121 pubmed publisher
Mohr M, Nielsen T, Weihe P, Thomsen J, Aquino G, Krustrup P, et al. Muscle ion transporters and antioxidative proteins have different adaptive potential in arm than in leg skeletal muscle with exercise training. Physiol Rep. 2017;5: pubmed publisher
Hostrup M, Onslev J, Jacobson G, Wilson R, Bangsbo J. Chronic ?2 -adrenoceptor agonist treatment alters muscle proteome and functional adaptations induced by high intensity training in young men. J Physiol. 2017;: pubmed publisher
Kleinert M, Parker B, Fritzen A, Knudsen J, Jensen T, Kjøbsted R, et al. Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice. J Physiol. 2017;595:4845-4855 pubmed publisher
Dion F, Dumayne C, Henley N, Beauchemin S, Arias E, Leblond F, et al. Mechanism of insulin resistance in a rat model of kidney disease and the risk of developing type 2 diabetes. PLoS ONE. 2017;12:e0176650 pubmed publisher
Fentz J, Kjøbsted R, Kristensen C, Hingst J, Birk J, Gudiksen A, et al. AMPKα is essential for acute exercise-induced gene responses but not for exercise training-induced adaptations in mouse skeletal muscle. Am J Physiol Endocrinol Metab. 2015;309:E900-14 pubmed publisher
Albers P, Bojsen Møller K, Dirksen C, Serup A, Kristensen D, Frystyk J, et al. Enhanced insulin signaling in human skeletal muscle and adipose tissue following gastric bypass surgery. Am J Physiol Regul Integr Comp Physiol. 2015;309:R510-24 pubmed publisher
Laye M, Nielsen M, Hansen L, Knudsen T, Pedersen B. Physical activity enhances metabolic fitness independently of cardiorespiratory fitness in marathon runners. Dis Markers. 2015;2015:806418 pubmed publisher
Hong Y, Frugier T, Zhang X, Murphy R, Lynch G, Betik A, et al. Glucose uptake during contraction in isolated skeletal muscles from neuronal nitric oxide synthase μ knockout mice. J Appl Physiol (1985). 2015;118:1113-21 pubmed publisher
Fentz J, Kjøbsted R, Birk J, Jordy A, Jeppesen J, Thorsen K, et al. AMPKα is critical for enhancing skeletal muscle fatty acid utilization during in vivo exercise in mice. FASEB J. 2015;29:1725-38 pubmed publisher
D Hulst G, Sylow L, Hespel P, Deldicque L. Acute systemic insulin intolerance does not alter the response of the Akt/GSK-3 pathway to environmental hypoxia in human skeletal muscle. Eur J Appl Physiol. 2015;115:1219-31 pubmed publisher
image
image 1 :
Invitrogen PA1-1065 image 1
product information
Product Type :
Antibody
Product Name :
GLUT4 Polyclonal Antibody
Catalog # :
PA1-1065
Quantity :
100 µg
Price :
US 450.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Rat
Applications :
Western Blot: 1:1,000
Species :
Rat
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
Immunogen :
Synthetic peptide corresponding to residues E(493) Q E V K P S T E L E Y L G P D E N D(509) of rat GLUT4.
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:1,000
Aliases :
glucose transporter 4; Glucose transporter 4 insuline-responsive; Glucose transporter 4, insuline-responsive; glucose transporter GLUT4; glucose transporter type 4; glucose transporter type 4, insulin-responsive; GLUT4; GLUT-4; GT2; insulin responsive glucose transporter; insulin-responsive glucose transporter; insulin-responsive glucose transporter type 4; MGC93607; SLC2A4; solute carrier family 2 member 4; solute carrier family 2 (facilitated glucose transporter), member 4; solute carrier family 2 , member 4; solute carrier family 2 member 4; solute carrier family 2, facilitated glucose transporter member 4
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA