This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TC10 Polyclonal Antibody
catalog :
PA1-1061
quantity :
100µg
price :
US 309.00
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunoprecipitation
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 7b
  • western blot; mouse; 1:1000; loading ...; fig 7b
Horsthemke M, Bachg A, Groll K, Moyzio S, Müther B, Hemkemeyer S, et al. Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion. J Biol Chem. 2017;292:7258-7273 pubmed publisher
product information
Product Type :
Antibody
Product Name :
TC10 Polyclonal Antibody
Catalog # :
PA1-1061
Quantity :
100µg
Price :
US 309.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunoprecipitation: Assay dependent, Western Blot: 1 µg/mL
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
TC10 has been classified as a member of the Rho family of GTPases and possesses characteristics most closely related to Cdc42. This family of proteins regulates a wide variety of cellular activity including cytoskeletal rearrangements, motility, proliferation and apoptosis. TC10 is predominately localized to the cell membrane and TC10 mRNA was most highly expressed in heart and skeletal muscle. Recent studies with TC10 mutations have demonstrated that TC10 is responsible for the activation of c-jun amino terminal kinase, the activation of serum response factor-dependent transcription, and the formation of long filopodia. In other studies, TC10 interacts with a similar subset of effectors as Cdc42, but does not react with WASP, MLK3, or ACK-1.
Immunogen :
Synthetic peptide corresponding D(136) P K T L A R L N D M K E K P I C(152) from human TC10.
Format :
Liquid
Applications w/Dilutions :
Immunoprecipitation: Assay dependent, Western Blot: 1 µg/mL
Aliases :
ARHQ, RASL7A, TC10, TC10A
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA