Perilipin 1 Polyclonal Antibody | Invitrogen PA1-1051 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Perilipin 1 Polyclonal Antibody

catalog :

PA1-1051

quantity :

100 µg

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 1d	Xu B, O DONNELL M, O Donnell J, Yu J, Zhang Y, Sartor M, et al. Adipogenic Differentiation of Thyroid Cancer Cells Through the Pax8-PPAR? Fusion Protein Is Regulated by Thyroid Transcription Factor 1 (TTF-1). J Biol Chem. 2016;291:19274-86 pubmed publisher
	Zhao D, Wu K, Sharma S, Xing F, Wu S, Tyagi A, et al. Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes. Nat Commun. 2022;13:7734 pubmed publisher
	Hu Y, Li X, Zhi X, Cong W, Huang B, Chen H, et al. RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss. EMBO Rep. 2021;22:e52481 pubmed publisher
	Kundimi S, Kavungala K, Sinha S, Tayi V, Kundurthi N, Golakoti T, et al. Combined extracts of Moringa oleifera, Murraya koeingii leaves, and Curcuma longa rhizome increases energy expenditure and controls obesity in high-fat diet-fed rats. Lipids Health Dis. 2020;19:198 pubmed publisher
	Zhang Y, Yu J, Lee C, Xu B, Sartor M, Koenig R. Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein. Oncotarget. 2015;6:40418-32 pubmed publisher

image

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product information

Product Type :

Antibody

Product Name :

Perilipin 1 Polyclonal Antibody

Catalog # :

PA1-1051

Quantity :

100 µg

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Mouse, Rat

Applications :

Immunocytochemistry: 2 µg/mL, Western Blot: 1:1,000-1:4,000

Species :

Mouse, Rat

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Adipose tissue is an energy reserve in animals and is strictly regulated in nondomestic species. Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), resistin, and perilipin. Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.

Immunogen :

Synthetic peptide corresponding to the residues C E(502) P I L G R T Q Y S Q L R K K S(517) of rat Perilipin A.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 µg/mL, Western Blot: 1:1,000-1:4,000

Aliases :

6030432J05Rik; adipocyte lipid droplet binding protein; FPLD4; Lipid droplet-associated protein; PERI; PERIA; perilipin; perilipin 1; perilipin A; perilipin B; perilipin-1; PLIN; PLIN1

more info or order :

Invitrogen product webpage