Synaptophysin Polyclonal Antibody | Invitrogen PA1-1043 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Synaptophysin Polyclonal Antibody

catalog :

PA1-1043

quantity :

100 µg

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine, domestic sheep

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:5000; loading ...; fig 1c	Sahasrabudhe A, Begum F, Guevara C, Morrison C, Hsiao K, Kezunovic N, et al. Cyfip1 Regulates SynGAP1 at Hippocampal Synapses. Front Synaptic Neurosci. 2020;12:581714 pubmed publisher
immunohistochemistry; mouse; fig 2d	Ling S, Dastidar S, Tokunaga S, Ho W, Lim K, Ilieva H, et al. Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis. elife. 2019;8: pubmed publisher
	D Ercole C, D Angelo P, Ruggieri V, Proietti D, Virtanen L, Parisi C, et al. Spatially resolved transcriptomics reveals innervation-responsive functional clusters in skeletal muscle. Cell Rep. 2022;41:111861 pubmed publisher
	Ang S, Crombie E, Dong H, Tan K, Hernando A, Yu D, et al. Muscle 4EBP1 activation modifies the structure and function of the neuromuscular junction in mice. Nat Commun. 2022;13:7792 pubmed publisher
	Quaglia F, Krishn S, Sossey Alaoui K, Rana P, Pluskota E, Park P, et al. The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancer. Sci Rep. 2022;12:18879 pubmed publisher
	Yilmaz C, Rogdakis T, Latorrata A, Thanou E, Karadima E, Papadimitriou E, et al. ENT-A010, a Novel Steroid Derivative, Displays Neuroprotective Functions and Modulates Microglial Responses. Biomolecules. 2022;12: pubmed publisher
	Xiang C, Chen P, Zhang Q, Li Y, Pan Y, Xie W, et al. Intestinal microbiota modulates adrenomedullary response through Nod1 sensing in chromaffin cells. iScience. 2021;24:102849 pubmed publisher
	Fonseca Ornelas L, Viennet T, Rovere M, Jiang H, Liu L, Nuber S, et al. Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson's disease. Cell Rep. 2021;36:109333 pubmed publisher
	Quaglia F, Krishn S, Wang Y, Goodrich D, McCue P, Kossenkov A, et al. Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression. PLoS ONE. 2021;16:e0244985 pubmed publisher
	Chand S, Jo A, Vellichirammal N, Gowen A, Guda C, Schaal V, et al. Comprehensive Characterization of Nanosized Extracellular Vesicles from Central and Peripheral Organs : Implications for Preclinical and Clinical Applications. ACS Appl Nano Mater. 2020;3:8906-8919 pubmed publisher
	Koller E, Gonzalez De La Cruz E, Weinrich M, Williams T, Cruz P, Ryu D, et al. Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy. Mol Neurobiol. 2020;: pubmed publisher
	Teoh J, Subramanian N, Pero M, Bartolini F, Amador A, Kanber A, et al. Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors. Neurobiol Dis. 2020;134:104632 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Synaptophysin Polyclonal Antibody

Catalog # :

PA1-1043

Quantity :

100 µg

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Human, Mouse, Ovine, Rat

Applications :

Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1:1,000

Species :

Bovine, Human, Mouse, Ovine, Rat

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.

Immunogen :

Synthetic peptide corresponding to residues G(253) P G G Y G P Q D S Y G P Q G G Y Q P D(272) of rat Synaptophysin.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1:1,000

Aliases :

A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1

more info or order :

Invitrogen product webpage