MBP Polyclonal Antibody | Invitrogen PA1-10008 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MBP Polyclonal Antibody

catalog :

PA1-10008

quantity :

100 µL

price :

US 440.00

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine, pigs

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - free floating section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig e9b	Kaya T, Mattugini N, Liu L, Ji H, Cantuti Castelvetri L, Wu J, et al. CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging. Nat Neurosci. 2022;25:1446-1457 pubmed publisher
	Guillemot Legris O, Girmahun G, Shipley R, Phillips J. Local Administration of Minocycline Improves Nerve Regeneration in Two Rat Nerve Injury Models. Int J Mol Sci. 2023;24: pubmed publisher
	Tringides C, Boulingre M, Khalil A, Lungjangwa T, Jaenisch R, Mooney D. Tunable Conductive Hydrogel Scaffolds for Neural Cell Differentiation. Adv Healthc Mater. 2023;12:e2202221 pubmed publisher
	Lim R, Al Dalahmah O, Wu J, Gold M, Reidling J, Tang G, et al. Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nat Commun. 2022;13:7791 pubmed publisher
	Jang J, Kim H, Seo D, Ki S, Park S, Choi S, et al. Whole-Brain Mapping of the Expression Pattern of T1R2, a Subunit Specific to the Sweet Taste Receptor. Front Neuroanat. 2021;15:751839 pubmed publisher
	Potratz M, Zaeck L, Weigel C, Klein A, Freuling C, Muller T, et al. Neuroglia infection by rabies virus after anterograde virus spread in peripheral neurons. Acta Neuropathol Commun. 2020;8:199 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MBP Polyclonal Antibody

Catalog # :

PA1-10008

Quantity :

100 µL

Price :

US 440.00

Clonality :

Polyclonal

Host :

Chicken

Reactivity :

Bovine, Human, Mouse, Porcine, Rat

Applications :

Immunocytochemistry: 1:2,000, Immunohistochemistry: 1:20,000, Western Blot: 1:10,000

Species :

Bovine, Human, Mouse, Porcine, Rat

Isotype :

IgY

Storage :

4° C

Description :

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.

Immunogen :

Full length purified myelin basic protein isolated from cow nerve

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:2,000, Immunohistochemistry: 1:20,000, Western Blot: 1:10,000

Aliases :

20 kDa microtubule-stabilizing protein; C76307; golli mbp; Golli-mbp; Golli-MBP; myelin basic protein; Golli-Mbp; myelin basic protein; myelin basic protein S; Hmbpr; MBP; MBP S; Mbps; MGC99675; microtubule-stabilizing protein; mld; MOBP; Myelin A1 protein; myelin basic protein; myelin basic protein Golli-mbp; myelin basic protein S; myelin deficient; myelin membrane encephalitogenic protein; Myelin P1 protein; myelin-associated oligodendrocyte basic protein; R75289; shi; shiverer; Unknown (protein for IMAGE:7984318); unnamed protein product

more info or order :

Invitrogen product webpage