MAP2 Polyclonal Antibody | Invitrogen PA1-10005 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MAP2 Polyclonal Antibody

catalog :

PA1-10005

quantity :

50 µL

price :

US 496.00

clonality :

polyclonal

host :

chicken

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 17

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:3000; loading ...; fig 3e	Easton A, Jensen M, Wang C, Hagedorn P, Li Y, WEED M, et al. Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies. Mol Ther Nucleic Acids. 2022;29:625-642 pubmed publisher
	Sulimai N, Brown J, Lominadze D. The Role of Nuclear Factor-Kappa B in Fibrinogen-Induced Inflammatory Responses in Cultured Primary Neurons. Biomolecules. 2022;12: pubmed publisher
	Liu L, Koo Y, Russell T, Yun Y. A Three-Dimensional Brain-on-a-Chip Using Human iPSC-Derived GABAergic Neurons and Astrocytes. Methods Mol Biol. 2022;2492:117-128 pubmed publisher
	Scalise S, Zannino C, Lucchino V, Lo Conte M, Scaramuzzino L, Cifelli P, et al. Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity. Biomedicines. 2022;10: pubmed publisher
	Ragauskas T, Rysevaite Kyguoliene K, Pauziene N, Inokaitis H, Pauza D. Chemical phenotypes of intrinsic cardiac neurons in the newborn pig (Sus scrofa domesticus Erxleben, 1777). J Morphol. 2022;283:51-65 pubmed publisher
	de Rus Jacquet A, Tancredi J, Lemire A, DeSantis M, Li W, O Shea E. The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson's disease. elife. 2021;10: pubmed publisher
	Hou X, Qiu Z, Xian Q, Kala S, Jing J, Wong K, et al. Precise Ultrasound Neuromodulation in a Deep Brain Region Using Nano Gas Vesicles as Actuators. Adv Sci (Weinh). 2021;8:e2101934 pubmed publisher
	Davis S, Roth J, Aljabi Q, Hakim A, Savell K, Day J, et al. Delivering progranulin to neuronal lysosomes protects against excitotoxicity. J Biol Chem. 2021;:100993 pubmed publisher
	Jeckel P, Kriebel M, Volkmer H. Autism Spectrum Disorder Risk Factor Met Regulates the Organization of Inhibitory Synapses. Front Mol Neurosci. 2021;14:659856 pubmed publisher
	Qiu Z, Kala S, Guo J, Xian Q, Zhu J, Zhu T, et al. Targeted Neurostimulation in Mouse Brains with Non-invasive Ultrasound. Cell Rep. 2020;32:108033 pubmed publisher
	Rush T, Roth J, Thompson S, Aldaher A, Cochran J, Roberson E. A peptide inhibitor of Tau-SH3 interactions ameliorates amyloid-β toxicity. Neurobiol Dis. 2020;134:104668 pubmed publisher
	Di Re J, Kayasandik C, Botello Lins G, Labate D, Laezza F. Imaging of the Axon Initial Segment. Curr Protoc Neurosci. 2019;89:e78 pubmed publisher
	Liu G, Thangavel R, Rysted J, Kim Y, Francis M, Adams E, et al. Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium. J Neurosci Res. 2019;97:1393-1413 pubmed publisher
	Kim Y, Liu G, Leugers C, Mueller J, Francis M, Hefti M, et al. Tau interacts with SHP2 in neuronal systems and in Alzheimer's disease. J Cell Sci. 2019;: pubmed publisher
	Koo Y, Hawkins B, Yun Y. Three-dimensional (3D) tetra-culture brain on chip platform for organophosphate toxicity screening. Sci Rep. 2018;8:2841 pubmed publisher
	Lin M, Wang Y, Wu W, Wolseley V, Tsai M, Radic V, et al. Zika Virus Infects Intermediate Progenitor Cells and Post-mitotic Committed Neurons in Human Fetal Brain Tissues. Sci Rep. 2017;7:14883 pubmed publisher
	Das D, Tapias V, D Aiuto L, Chowdari K, Francis L, Zhi Y, et al. Genetic and morphological features of human iPSC-derived neurons with chromosome 15q11.2 (BP1-BP2) deletions. Mol Neuropsychiatry. 2015;1:116-123 pubmed

image

image 1 :

image 2 :

product information

Product Type :

Antibody

Product Name :

MAP2 Polyclonal Antibody

Catalog # :

PA1-10005

Quantity :

50 µL

Price :

US 496.00

Clonality :

Polyclonal

Host :

Chicken

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:5,000-1:10,000, Immunohistochemistry: 1:5,000-1:10,000, Western Blot: 1:20,000-1:50,000

Species :

Human, Mouse, Rat

Isotype :

IgY

Storage :

4° C

Description :

MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).

Immunogen :

Mix of recombinant human constructs of projection domain sequences, amino acids 235-1588.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:5,000-1:10,000, Immunohistochemistry: 1:5,000-1:10,000, Western Blot: 1:20,000-1:50,000

Aliases :

a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2

more info or order :

Invitrogen product webpage