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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Vimentin Polyclonal Antibody
catalog :
PA1-10003
quantity :
100 µL
price :
US 516.00
clonality :
polyclonal
host :
chicken
conjugate :
nonconjugated
reactivity :
human, mouse, rat, chicken, bovine, pigs , domestic horse
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 8
Published Application/Species/Sample/Dilution | Reference |
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product information
Product Type :
Antibody
Product Name :
Vimentin Polyclonal Antibody
Catalog # :
PA1-10003
Quantity :
100 µL
Price :
US 516.00
Clonality :
Polyclonal
Host :
Chicken
Reactivity :
Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Applications :
Immunocytochemistry: 1:5,000, Western Blot: 1:10,000
Species :
Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Isotype :
IgY
Storage :
4° C
Description :
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.
Immunogen :
Full length recombinant human vimentin
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:5,000, Western Blot: 1:10,000
Aliases :
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus
more info or order :
company information

Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
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