LIN28A Polyclonal Antibody | Invitrogen PA1-096X product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LIN28A Polyclonal Antibody

catalog :

PA1-096X

quantity :

20 uL

price :

US 177.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

citations: 5

Reference
Muneer R, Qazi R, Fatima A, Ahmad W, Salim A, Dini L, et al. Wnt signaling pathway inhibitor promotes mesenchymal stem cells differentiation into cardiac progenitor cells in vitro and improves cardiomyopathy in vivo. World J Stem Cells. 2023;15:821-841 pubmed publisher
Fahim I, Ishaque A, Ramzan F, Shamsuddin S, Ali A, Salim A, et al. Overexpression of OLIG2 and MYT1L Transcription Factors Enhance the Differentiation Potential of Human Mesenchymal Stem Cells into Oligodendrocytes. Curr Issues Mol Biol. 2023;45:4100-4123 pubmed publisher
Broughton K, Esquer C, Echeagaray O, Firouzi F, Shain G, Ebeid D, et al. Surface Lin28A expression consistent with cellular stress parallels indicators of senescence. Cardiovasc Res. 2023;119:743-758 pubmed publisher
Wang Y, Liu J, Wu G, Yang F. Manipulations in HIWI level exerts influence on the proliferation of human non-small cell lung cancer cells. Exp Ther Med. 2016;11:1971-1976 pubmed
Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher

product information

Product Type :

Antibody

Product Name :

LIN28A Polyclonal Antibody

Catalog # :

PA1-096X

Quantity :

20 uL

Price :

US 177.00

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1:100, Immunocytochemistry: 1:100-1:200, Immunohistochemistry (Paraffin): 1:20-1:50, Immunoprecipitation: 5 ug, 1:1,000, Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.

Immunogen :

Full-length human recombinant protein expressed in bacteria

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:100, Immunocytochemistry: 1:100-1:200, Immunohistochemistry (Paraffin): 1:20-1:50, Immunoprecipitation: 5 ug, 1:1,000, Western Blot: 1:1,000

Aliases :

AL024421; CSDD1; ENSMUSG00000070700; FLJ12457; Gm10299; Lin28; LIN-28; lin-28 homolog A; lin-28 homolog A (C. elegans); Lin28a; lin-28A; Protein lin-28 homolog A; RGD1566408; RNA-binding protein LIN-28; sb:cb650; si:ch211-232d9.4; similar to RNA-binding protein LIN-28; testis expressed gene 17; testis-expressed protein 17; Tex17; ZCCHC1; zgc:55584; Zinc finger CCHC domain-containing protein 1; zinc finger, CCHC domain containing 1