This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SOX2 Polyclonal Antibody
catalog :
PA1-094X
quantity :
20 uL
price :
US 187.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 36
Reference
Prajapati K, Kumar S. Loss of miR-6844 alters stemness/self-renewal and cancer hallmark(s) markers through CD44-JAK2-STAT3 signaling axis in breast cancer stem-like cells. J Cell Biochem. 2023;124:1186-1202 pubmed publisher
Mendivil Perez M, Velez Pardo C, Lopera F, Kosik K, Jimenez Del Rio M. PSEN1 E280A Cholinergic-like Neurons and Cerebral Spheroids Derived from Mesenchymal Stromal Cells and from Induced Pluripotent Stem Cells Are Neuropathologically Equivalent. Int J Mol Sci. 2023;24: pubmed publisher
Zhang T, Xu P. The role of Eya1 and Eya2 in the taste system of mice from embryonic stage to adulthood. Front Cell Dev Biol. 2023;11:1126968 pubmed publisher
Su P, Lee W, Zernant J, Tsang S, Nagasaki T, Corneo B, et al. Establishment of the iPSC line CUIMCi005-A from a patient with Stargardt disease for retinal organoid culture. Stem Cell Res. 2022;65:102973 pubmed publisher
Stasikowska Kanicka O, Woskowicz M, Ulewicz K, Danilewicz M, W x105 growska Danilewicz M. Close relationship between TAZhigh/SOX2high co-localization and metastasis in oral squamous cell carcinoma. Pol J Pathol. 2021;72:229-236 pubmed publisher
Paterson C, Kilmister E, Brasch H, Bockett N, Patel J, Paterson E, et al. Cell Populations Expressing Stemness-Associated Markers in Lung Adenocarcinoma. Life (Basel). 2021;11: pubmed publisher
Humphries F, Chang McDonald B, Patel J, Bockett N, Paterson E, Davis P, et al. Cathepsins B, D, and G Are Expressed in Metastatic Head and Neck Cutaneous Squamous Cell Carcinoma. Front Oncol. 2021;11:690460 pubmed publisher
Haldipur P, Bernardo S, Aldinger K, Sivakumar T, Millman J, Sjoboen A, et al. Evidence of disrupted rhombic lip development in the pathogenesis of Dandy-Walker malformation. Acta Neuropathol. 2021;142:761-776 pubmed publisher
Quintero Espinosa D, Soto Mercado V, Quintero Quinchia C, Mendivil Perez M, Velez Pardo C, Jimenez Del Rio M. Latent Tri-lineage Potential of Human Menstrual Blood-Derived Mesenchymal Stromal Cells Revealed by Specific In Vitro Culture Conditions. Mol Neurobiol. 2021;58:5194-5209 pubmed publisher
Tekel S, Brookhouser N, Standage Beier K, Wang X, Brafman D. Cytosine and adenosine base editing in human pluripotent stem cells using transient reporters for editing enrichment. Nat Protoc. 2021;16:3596-3624 pubmed publisher
Luke Krishnan C, Brasch H, Patel J, Bockett N, Paterson E, Davis P, et al. Stemness-Associated Markers Are Expressed in Extracranial Arteriovenous Malformation. Front Surg. 2021;8:621089 pubmed publisher
Kilmister E, Patel J, Bockett N, Chang McDonald B, Sim D, Wickremesekera A, et al. Embryonic stem cell-like subpopulations are present within Schwannoma. J Clin Neurosci. 2020;81:201-209 pubmed publisher
Kilmister E, Patel J, van Schaijik B, Bockett N, Brasch H, Paterson E, et al. Cancer Stem Cell Subpopulations Are Present Within Metastatic Head and Neck Cutaneous Squamous Cell Carcinoma. Front Oncol. 2020;10:1091 pubmed publisher
Chao X, Yi L, Lan L, Wei H, Wei D. Long-term PM2.5 exposure increases the risk of non-small cell lung cancer (NSCLC) progression by enhancing interleukin-17a (IL-17a)-regulated proliferation and metastasis. Aging (Albany NY). 2020;12:11579-11602 pubmed publisher
Menendez S, Rey V, Martinez Cruzado L, Gonzalez M, Morales Molina Á, Santos L, et al. SOX2 Expression and Transcriptional Activity Identifies a Subpopulation of Cancer Stem Cells in Sarcoma with Prognostic Implications. Cancers (Basel). 2020;12: pubmed publisher
Yoganandarajah V, Patel J, van Schaijik B, Bockett N, Brasch H, Paterson E, et al. Identification of Cancer Stem Cell Subpopulations in Head and Neck Metastatic Malignant Melanoma. Cells. 2020;9: pubmed publisher
Koh S, Brasch H, de Jongh J, Itinteang T, Tan S. Cancer stem cell subpopulations in moderately differentiated head and neck cutaneous squamous cell carcinoma. Heliyon. 2019;5:e02257 pubmed publisher
Tan E, Brasch H, Davis P, Itinteang T, Tan S. Embryonic Stem Cell-like Population within Venous Malformation Expresses the Renin-Angiotensin System. Plast Reconstr Surg Glob Open. 2019;7:e2170 pubmed publisher
Roy A, Murphy R, Deng M, MacDonald J, Bammler T, Aldinger K, et al. PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice. elife. 2019;8: pubmed publisher
Papali i Curtin J, Brasch H, van Schaijik B, de Jongh J, Marsh R, Tan S, et al. Expression of Components of the Renin-Angiotensin System in Pyogenic Granuloma. Front Surg. 2019;6:13 pubmed publisher
Miterko L, White J, Lin T, Brown A, O Donovan K, Sillitoe R. Persistent motor dysfunction despite homeostatic rescue of cerebellar morphogenesis in the Car8 waddles mutant mouse. Neural Dev. 2019;14:6 pubmed publisher
Shivapathasundram G, Wickremesekera A, Brasch H, Marsh R, Tan S, Itinteang T. Expression of Embryonic Stem Cell Markers on the Microvessels of WHO Grade I Meningioma. Front Surg. 2018;5:65 pubmed publisher
Mollica P, Zamponi M, Reid J, Sharma D, White A, Ogle R, et al. Epigenetic alterations mediate iPSC-induced normalization of DNA repair gene expression and TNR stability in Huntington's disease cells. J Cell Sci. 2018;131: pubmed publisher
Petrella R, Mollica P, Zamponi M, Reid J, Xiao S, Bruno R, et al. 3D bioprinter applied picosecond pulsed electric fields for targeted manipulation of proliferation and lineage specific gene expression in neural stem cells. J Neural Eng. 2018;15:056021 pubmed publisher
Humphries H, Wickremesekera S, Marsh R, Brasch H, Mehrotra S, Tan S, et al. Characterization of Cancer Stem Cells in Colon Adenocarcinoma Metastasis to the Liver. Front Surg. 2017;4:76 pubmed publisher
Tan E, Siljee S, Brasch H, Enríquez S, Tan S, Itinteang T. Embryonic Stem Cell-Like Subpopulations in Venous Malformation. Front Med (Lausanne). 2017;4:162 pubmed publisher
Zhang T, Xu J, Maire P, Xu P. Six1 is essential for differentiation and patterning of the mammalian auditory sensory epithelium. PLoS Genet. 2017;13:e1006967 pubmed publisher
Ram R, Brasch H, Dunne J, Davis P, Tan S, Itinteang T. Cancer Stem Cells in Moderately Differentiated Lip Squamous Cell Carcinoma Express Components of the Renin-Angiotensin System. Front Surg. 2017;4:30 pubmed publisher
Ram R, Brasch H, Dunne J, Davis P, Tan S, Itinteang T. The Identification of Three Cancer Stem Cell Subpopulations within Moderately Differentiated Lip Squamous Cell Carcinoma. Front Surg. 2017;4:12 pubmed publisher
Koh S, On N, Brasch H, Chibnall A, Armstrong J, Davis P, et al. Embryonic Stem Cell-like Population in Dupuytren's Disease. Plast Reconstr Surg Glob Open. 2016;4:e1064 pubmed
Featherston T, Yu H, Dunne J, Chibnall A, Brasch H, Davis P, et al. Cancer Stem Cells in Moderately Differentiated Buccal Mucosal Squamous Cell Carcinoma Express Components of the Renin-Angiotensin System. Front Surg. 2016;3:52 pubmed
Bradshaw A, Wickremesekera A, Brasch H, Chibnall A, Davis P, Tan S, et al. Glioblastoma Multiforme Cancer Stem Cells Express Components of the Renin-Angiotensin System. Front Surg. 2016;3:51 pubmed
BRADSHAW A, Wickremesekera A, Brasch H, Chibnall A, Davis P, Tan S, et al. Cancer Stem Cells in Glioblastoma Multiforme. Front Surg. 2016;3:48 pubmed publisher
Itinteang T, Dunne J, Chibnall A, Brasch H, Davis P, Tan S. Cancer stem cells in moderately differentiated oral tongue squamous cell carcinoma express components of the renin-angiotensin system. J Clin Pathol. 2016;69:942-5 pubmed publisher
Martinez Cruzado L, Tornin J, Santos L, Rodriguez A, Garcia Castro J, Morís F, et al. Aldh1 Expression and Activity Increase During Tumor Evolution in Sarcoma Cancer Stem Cell Populations. Sci Rep. 2016;6:27878 pubmed publisher
Baillie R, Itinteang T, Yu H, Brasch H, Davis P, Tan S. Cancer stem cells in moderately differentiated oral tongue squamous cell carcinoma. J Clin Pathol. 2016;69:742-4 pubmed publisher
product information
Product Type :
Antibody
Product Name :
SOX2 Polyclonal Antibody
Catalog # :
PA1-094X
Quantity :
20 uL
Price :
US 187.00
Clonality :
Polyclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Fish, Human, Mouse
Applications :
CUT&RUN: 1:100, Flow Cytometry: 1:100, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Frozen): 1:50-1:500, Immunohistochemistry (Paraffin): 1:50-1:500, Immunoprecipitation: 5 ug, 1:1,000, Western Blot: 1:1,000
Species :
Fish, Human, Mouse
Isotype :
IgG
Storage :
-20 C
Description :
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
Immunogen :
Full-length human recombinant protein expressed in bacteria
Format :
Liquid
Applications w/Dilutions :
CUT&RUN: 1:100, Flow Cytometry: 1:100, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Frozen): 1:50-1:500, Immunohistochemistry (Paraffin): 1:50-1:500, Immunoprecipitation: 5 ug, 1:1,000, Western Blot: 1:1,000
Aliases :
ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA