COPII Polyclonal Antibody | Invitrogen PA1-069A product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

COPII Polyclonal Antibody

catalog :

PA1-069A

quantity :

100 µg

price :

US 450

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, fruit fly

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; fruit fly ; 1:500; fig 1c	Liu M, Feng Z, Ke H, Liu Y, Sun T, Dai J, et al. Tango1 spatially organizes ER exit sites to control ER export. J Cell Biol. 2017;216:1035-1049 pubmed publisher
	Wang R, Miao G, Shen J, Fortier T, Baehrecke E. ESCRT dysfunction compromises endoplasmic reticulum maturation and autophagosome biogenesis in Drosophila. Curr Biol. 2022;32:1262-1274.e4 pubmed publisher
	Wei W, Liu Z, Zhang C, Khoriaty R, Zhu M, Zhang B. A common human missense mutation of vesicle coat protein SEC23B leads to growth restriction and chronic pancreatitis in mice. J Biol Chem. 2022;298:101536 pubmed publisher
	Moreira D, Suzuki A, Silva A, Varella Branco E, Meneghetti M, Kobayashi G, et al. Neuroprogenitor Cells From Patients With TBCK Encephalopathy Suggest Deregulation of Early Secretory Vesicle Transport. Front Cell Neurosci. 2021;15:803302 pubmed publisher
	BOGDANOV V, Soltisz A, Moise N, Sakuta G, Orengo B, Janssen P, et al. Distributed synthesis of sarcolemmal and sarcoplasmic reticulum membrane proteins in cardiac myocytes. Basic Res Cardiol. 2021;116:63 pubmed publisher
	Stefanovic B, Stefanovic L, Manojlovic Z. Imaging of type I procollagen biosynthesis in cells reveals biogenesis in highly organized bodies; Collagenosomes. Matrix Biol Plus. 2021;12:100076 pubmed publisher
	Mazzulli J, Zunke F, Isacson O, Studer L, Krainc D. Î±-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models. Proc Natl Acad Sci U S A. 2016;113:1931-6 pubmed publisher

product information

Product Type :

Antibody

Product Name :

COPII Polyclonal Antibody

Catalog # :

PA1-069A

Quantity :

100 µg

Price :

US 450

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:10-1:200, Immunofluorescence: 1:10-1:200, Western Blot: 2 µg/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Coatomer proteins are involved in regulating transport between the endoplasmic reticulum (ER) and the Golgi complex and in intra-Golgi transport. There exist two coatomer-protein mechanisms (COPI and COPII) and although they have mechanistic parallels, they are molecularly distinct. The COPI coat is comprised of seven subunits (alpha-, beta-, beta'-, gamma-, delta-, epsilon-, and zeta-COP) in a complex called coatomer. Assembly of the coatomer (COPI) onto non-clathrin coated vesicles is regulated by ADP-ribosylation factor (ARF). Vesicle formation, budding, fusion, and disassembly is dependent on GDP-GTP exchange, COPI, and ARF. COPI has been shown to facilitate retrograde intracellular transport from the ER to the Golgi complex. By contrast, COPII facilitates anterograde transport between these subcellular organelles. COPII has been shown to be independently and selectively recruited to the ER relative to COPI subunits. COPII consists of three parts: Sar1p and the two protein complexes, Sec23p-Sec24p and Sec13p-Sec31p.

Immunogen :

Synthetic peptide corresponding to residues M(1) T T Y L E F I Q Q N E E R D G V R (18) C of rat COPII.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:10-1:200, Immunofluorescence: 1:10-1:200, Western Blot: 2 µg/mL

Aliases :

1110003H02Rik; 1810024J13Rik; ABP125; ABP130; AU042160; CLSD; cop ii; D3S1231E; GATOR complex protein SEC13; hSec23A; HSPC275; HSPC334; KIAA0905; Msec23; npp-20; Protein SEC13 homolog; protein transport protein Sec23A; Protein transport protein Sec24A; protein transport protein Sec31A; Sec13; SEC13 homolog; SEC13 homolog (S. cerevisiae); SEC13 homolog, nuclear pore and COPII coat complex component; SEC13 homolog, nuclear pore and COPII coating complex component; SEC13 related; SEC13A; SEC13L1; SEC13-like 1; SEC13-like 1 isoform; SEC13-like protein 1; SEC13R; SEC13-related protein; Sec23; Sec23 homolog A (S. cerevisiae); Sec23 homolog A, coat complex II component; Sec23 homolog A, COPII coat complex component; SEC23A; SEC23A (S. cerevisiae); Sec23r; SEC23-related protein A; SEC24 family member A; SEC24 family, member A; SEC24 homolog A, COPII coat complex component; SEC24 related gene family, member A; Sec24 related gene family, member A (S. cerevisiae); SEC24A; SEC24-related protein A; Sec31 homolog A (S. cerevisiae); SEC31 homolog A, COPII coat complex component; SEC31 homolog A, COPII coating complex component; Sec31a; Sec31l1; SEC31-like 1; SEC31-like protein 1; SEC31-related protein A; VAP1; vesicle associated protein; Vesicle-associated protein 1; web1-like protein; yeast Sec31p homolog

more info or order :

Invitrogen product webpage