product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Adiponectin Polyclonal Antibody
catalog :
PA1-054
quantity :
200 µg
price :
US 471
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunocytochemistry, immunoprecipitation, blocking or activating experiments
more info or order :
Invitrogen product webpage
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 4b
Durcin M, Fleury A, Taillebois E, Hilairet G, Krupova Z, Henry C, et al. Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles. J Extracell Vesicles. 2017;6:1305677 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 5b
Chen J, Jian D, Lien C, Lin Y, Ting C, Chen L, et al. Adipocytes play an etiological role in the podocytopathy of high-fat diet-fed rats. J Endocrinol. 2016;231:109-120 pubmed
Wan Q, Huang B, Li T, Xiao Y, He Y, Du W, et al. Selective targeting of visceral adiposity by polycation nanomedicine. Nat Nanotechnol. 2022;17:1311-1321 pubmed publisher
Frei I, Weissenberger D, Ritz D, Heusermann W, Colombi M, Shimobayashi M, et al. Adipose mTORC2 is essential for sensory innervation in white adipose tissue and whole-body energy homeostasis. Mol Metab. 2022;65:101580 pubmed publisher
Prideaux M, Wright C, Noonan M, Yi X, Clinkenbeard E, Mével E, et al. Generation of two multipotent mesenchymal progenitor cell lines capable of osteogenic, mature osteocyte, adipogenic, and chondrogenic differentiation. Sci Rep. 2021;11:22593 pubmed publisher
Lin J, Huang L, Li Y, Zhang P, Yu Q, Yang Q. Bacillus subtilis Spore-Trained Dendritic Cells Enhance the Generation of Memory T Cells via ICAM1. Cells. 2021;10: pubmed publisher
Aaron N, Kraakman M, Zhou Q, Liu Q, Costa S, Yang J, et al. Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells. elife. 2021;10: pubmed publisher
Li J, Li E, Czepielewski R, Chi J, Guo X, Han Y, et al. Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells. Cell Metab. 2021;33:1449-1465.e6 pubmed publisher
Burrell J, Stephens J. KAT8, lysine acetyltransferase 8, is required for adipocyte differentiation in vitro. Biochim Biophys Acta Mol Basis Dis. 2021;1867:166103 pubmed publisher
Ma O, Le T, Talbott G, HoangThao Nguyen T, Ha D, Ho L. Sirt3 regulates adipogenesis and adipokine secretion via its enzymatic activity. Pharmacol Res Perspect. 2020;8:e00670 pubmed publisher
Gunn K, Roberts B, Wang F, Strauss J, Borgnia M, Egelman E, et al. The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage. Proc Natl Acad Sci U S A. 2020;117:10254-10264 pubmed publisher
Sen B, Paradise C, Xie Z, Sankaran J, Uzer G, Styner M, et al. β-Catenin Preserves the Stem State of Murine Bone Marrow Stromal Cells Through Activation of EZH2. J Bone Miner Res. 2020;35:1149-1162 pubmed publisher
Burrell J, Richard A, King W, Stephens J. Mitochondrial Pyruvate Carriers are not Required for Adipogenesis but are Regulated by High-Fat Feeding in Brown Adipose Tissue. Obesity (Silver Spring). 2020;28:293-302 pubmed publisher
Manieri E, Herrera Melle L, Mora A, Tomás Loba A, Leiva Vega L, Fernández D, et al. Adiponectin accounts for gender differences in hepatocellular carcinoma incidence. J Exp Med. 2019;216:1108-1119 pubmed publisher
Jager M, Lee M, Li C, Farmer S, Fried S, Layne M. Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue. PLoS ONE. 2018;13:e0197777 pubmed publisher
Obata Y, Kita S, Koyama Y, Fukuda S, Takeda H, Takahashi M, et al. Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release. JCI Insight. 2018;3: pubmed publisher
Kraakman M, Liu Q, Postigo Fernandez J, Ji R, Kon N, Larrea D, et al. PPAR? deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. J Clin Invest. 2018;128:2600-2612 pubmed publisher
Tran K, Fitzgibbons T, Min S, DeSouza T, Corvera S. Distinct adipocyte progenitor cells are associated with regional phenotypes of perivascular aortic fat in mice. Mol Metab. 2018;9:199-206 pubmed publisher
Thompson W, Yen S, Uzer G, Xie Z, Sen B, Styner M, et al. LARG GEF and ARHGAP18 orchestrate RhoA activity to control mesenchymal stem cell lineage. Bone. 2018;107:172-180 pubmed publisher
Ronkainen J, Huusko T, Soininen R, Mondini E, Cinti F, Mäkelä K, et al. Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue. Sci Rep. 2015;5:9233 pubmed publisher
image
image 1 :
Invitrogen PA1-054 image 1
product information
Product Type :
Antibody
Product Name :
Adiponectin Polyclonal Antibody
Catalog # :
PA1-054
Quantity :
200 µg
Price :
US 471
Clonality :
Polyclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Mouse
Applications :
Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunoprecipitation: Assay dependent, Western Blot: 2 µg/mL
Species :
Mouse
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates the metabolism of lipids and glucose. Adiponectin has been shown to play a role in various physiological processes including homeostasis and obesity. Decreased levels of adiponectin are associated with obese individuals as well as insulin resistance and hyperinsulinemia (type 2 diabetes). In mice adiponectin has been shown to improve insulin signaling, thus ameliorating insulin resistance. Through activation of AMP kinase and PPAR-alpha, adiponectin can increase fatty acid transport, oxidation, and dissipation in skeletal muscle, leading to a reduction of intramyocellular lipid levels and thus improved insulin signaling.
Immunogen :
Synthetic peptides corresponding to the residues E(18) D D V T T T E E L A P A L V(32) and F(187) T Y D Q Y Q E K N V D Q A(200) of mouse Adiponectin.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunoprecipitation: Assay dependent, Western Blot: 2 µg/mL
Aliases :
30 kDa adipocyte complement-related protein; 30kDa; Acdc; Acrp30; Ad; adipo; adipocyte complement related protein; adipocyte complement related protein of 30 kDa; adipocyte complement-related 30 kDa protein; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ; adiponectin; adiponectin, C1Q and collagen domain containing; Adipoq; Adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; ADIPQTL1; ADPIOQ; ADPN; APM1; APM-1; APN; GBP28; Gelatin-binding protein; gelatin-binding protein 28; LOC100009027
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA