beta-1 Adrenergic Receptor Polyclonal Antibody | Invitrogen PA1-049 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

beta-1 Adrenergic Receptor Polyclonal Antibody

catalog :

PA1-049

quantity :

100 uL

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 14

Reference
Ge M, Wu L, He F, Tai Y, Fang R, Han D, et al. CP-25 inhibits the hyperactivation of rheumatic synoviocytes by suppressing the switch in Gαs-Gαi coupling to the β2-adrenergic receptor. Cell Commun Signal. 2023;21:346 pubmed publisher
Haugsten Hansen M, Sadredini M, Hasic A, Anderson M, Sjaastad I, Korseberg Stokke M. CaMKII and reactive oxygen species contribute to early reperfusion arrhythmias, but oxidation of CaMKIIδ at methionines 281/282 is not a determining factor. J Mol Cell Cardiol. 2023;175:49-61 pubmed publisher
Ren L, Thai P, Gopireddy R, Timofeyev V, Ledford H, Woltz R, et al. Adenylyl cyclase isoform 1 contributes to sinoatrial node automaticity via functional microdomains. JCI Insight. 2022;7: pubmed publisher
Osorio Conles x, Olbeyra R, Moiz xe9 V, Ibarzabal A, Gir xf3 O, Viaplana J, et al. Positive Effects of a Mediterranean Diet Supplemented with Almonds on Female Adipose Tissue Biology in Severe Obesity. Nutrients. 2022;14: pubmed publisher
Chen Y, Song Q, Colucci P, Maltese F, Siller Pérez C, Prins K, et al. Basolateral amygdala activation enhances object recognition memory by inhibiting anterior insular cortex activity. Proc Natl Acad Sci U S A. 2022;119:e2203680119 pubmed publisher
Benton K, Wheeler D, Kurtoglu B, Ansari M, Cibich D, Gonzalez D, et al. Norepinephrine activates β1 -adrenergic receptors at the inner nuclear membrane in astrocytes. Glia. 2022;70:1777-1794 pubmed publisher
Lee H, Jin B, Park M, Seo K, Jeong Y, Choi S, et al. Deletion of adipose triglyceride lipase abolishes blood flow increase after β3-adrenergic stimulation in visceral adipose tissue of mice. Korean J Physiol Pharmacol. 2021;25:355-363 pubmed publisher
Funato Y, Yamazaki D, Okuzaki D, Yamamoto N, Miki H. Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure. Nat Commun. 2021;12:3683 pubmed publisher
Danielsen T, Sadredini M, Manotheepan R, Aronsen J, Frisk M, Hansen M, et al. Exercise Training Stabilizes RyR2-Dependent Ca2+ Release in Post-infarction Heart Failure. Front Cardiovasc Med. 2020;7:623922 pubmed publisher
Wang X, Fitts R. Cardiomyocyte slowly activating delayed rectifier potassium channel: regulation by exercise and β-adrenergic signaling. J Appl Physiol (1985). 2020;128:1177-1185 pubmed publisher
Cannavo A, Marzano F, Elia A, Liccardo D, Bencivenga L, Gambino G, et al. Aldosterone Jeopardizes Myocardial Insulin and β-Adrenergic Receptor Signaling via G Protein-Coupled Receptor Kinase 2. Front Pharmacol. 2019;10:888 pubmed publisher
Schinner C, Erber B, Yeruva S, Waschke J. Regulation of cardiac myocyte cohesion and gap junctions via desmosomal adhesion. Acta Physiol (Oxf). 2019;226:e13242 pubmed publisher
Tyurin Kuzmin P, Chechekhin V, Ivanova A, Dyikanov D, Sysoeva V, Kalinina N, et al. Noradrenaline Sensitivity Is Severely Impaired in Immortalized Adipose-Derived Mesenchymal Stem Cell Line. Int J Mol Sci. 2018;19: pubmed publisher
Bober S, Ciriello J, Jones D. Atrial arrhythmias and autonomic dysfunction in rats exposed to chronic intermittent hypoxia. Am J Physiol Heart Circ Physiol. 2018;314:H1160-H1168 pubmed publisher

product information

Product Type :

Antibody

Product Name :

beta-1 Adrenergic Receptor Polyclonal Antibody

Catalog # :

PA1-049

Quantity :

100 uL

Price :

US 451.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 1:100, Immunohistochemistry: Assay-dependent, Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family. Nine receptor subtypes have been identified thus far including three alpha-1 AR subtypes (1A/D, 1B, and 1C), three alpha-2 ARs (2A, 2B, and 2C), and three beta AR subtypes (1, 2, and 3). ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence. BARs participate in diverse processes including development, behavior, cardiac function, smooth muscle tone, and metabolism. In gene-knockout experiments, the majority of mice that lack the B1AR gene die prenatally and those that do survive until adulthood display abnormal cardiac function. Other studies have shown that the direct regulation of cardiac B1AR density by thyroid hormones occurs at the transcriptional level and is modulated by the catecholamine sensitive-adenylyl cyclase system. Evidence for the effects of cAMP on B1AR regulation has come from a study of members of the cAMP response element (CRE) modulator (CREM) family of transcription factors in transformed cell lines.

Immunogen :

Synthetic peptide corresponding to residues H(394) G D R P R A S G C L A R A G(408) of mouse B1AR.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunohistochemistry: Assay-dependent, Western Blot: 1:1,000

Aliases :

Adrb1; Adrb-1; ADRB1R; adrenergic receptor, beta 1; adrenergic, beta-1-, receptor; adrenoceptor beta 1; B1AR; beta 1-adrenergic receptor beta 1-AR; beta 1-AR; beta-1 adrenergic receptor; Beta-1 adrenoceptor; beta-1 adrenoreceptor; BETA1AR; beta-AR; cardiac beta adrenergic receptor; RATB1AR; RHR