alpha-2a Adrenergic Receptor Polyclonal Antibody | Invitrogen PA1-048 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

alpha-2a Adrenergic Receptor Polyclonal Antibody

catalog :

PA1-048

quantity :

100 µL

price :

US 430

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; fig 3c	Bellono N, Bayrer J, Leitch D, Castro J, Zhang C, O Donnell T, et al. Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways. Cell. 2017;170:185-198.e16 pubmed publisher
immunohistochemistry - frozen section; human; 1:100; fig s10	Liu S, Nowakowski T, Pollen A, Lui J, Horlbeck M, Attenello F, et al. Single-cell analysis of long non-coding RNAs in the developing human neocortex. Genome Biol. 2016;17:67 pubmed publisher
	Alhamyani A, Napit P, Bheemanapally K, Sylvester P, Briski K. Singular versus combinatory glucose-sensitive signal control of metabolic sensor protein profiles in hypothalamic astrocyte cultures from each sex. Transl Neurosci. 2022;13:408-420 pubmed publisher
	Romeo I, Vallarino G, Turrini F, Roggeri A, Olivero G, Boggia R, et al. Presynaptic Release-Regulating Alpha2 Autoreceptors: Potential Molecular Target for Ellagic Acid Nutraceutical Properties. Antioxidants (Basel). 2021;10: pubmed publisher
	Despain K, Rosenfeld C, Huebinger R, Wang X, Jay J, Radhakrishnan R, et al. Carotid smooth muscle contractility changes after severe burn. Sci Rep. 2021;11:18094 pubmed publisher
	Ibrahim M, Bheemanapally K, Sylvester P, Briski K. Norepinephrine Regulation of Adrenergic Receptor Expression, 5' AMP-Activated Protein Kinase Activity, and Glycogen Metabolism and Mass in Male Versus Female Hypothalamic Primary Astrocyte Cultures. ASN Neuro. 2020;12:1759091420974134 pubmed publisher
	Eagle A, Manning C, Williams E, Bastle R, Gajewski P, Garrison A, et al. Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidance. Nat Commun. 2020;11:4484 pubmed publisher
	Chia J, Izham N, Farouk A, Sulaiman M, Mustafa S, Hutchinson M, et al. Zerumbone Modulates α2A-Adrenergic, TRPV1, and NMDA NR2B Receptors Plasticity in CCI-Induced Neuropathic Pain In Vivo and LPS-Induced SH-SY5Y Neuroblastoma In Vitro Models. Front Pharmacol. 2020;11:92 pubmed publisher
	Cortada M, Levano S, Bodmer D. Brimonidine Protects Auditory Hair Cells from in vitro-Induced Toxicity of Gentamicin. Audiol Neurootol. 2017;22:125-134 pubmed publisher

product information

Product Type :

Antibody

Product Name :

alpha-2a Adrenergic Receptor Polyclonal Antibody

Catalog # :

PA1-048

Quantity :

100 µL

Price :

US 430

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:500

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Alpha-2-adrenergic receptors (ADRA2A) are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. ADRA2A mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G protein. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system.

Immunogen :

Synthetic peptide corressponding to residues R(218) I Y Q I A K R R T R V P P S R R G(235) of the 3rd intracellular loop of human A2AAR.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:500

Aliases :

ADRA2; Adra-2; ADRA2A; Adra-2a; ADRA2R; ADRAR; adrenergic receptor, alpha 2a; adrenergic, alpha-2A-, receptor; adrenoceptor alpha 2A; alpha(2A)AR; Alpha-2 adrenergic receptor subtype C10; alpha2A; Alpha-2A adrenergic receptor; alpha-2A adrenoceptor; Alpha-2A adrenoreceptor; alpha2A-adrenergic receptor; ALPHA2AAR; alpha-2AAR; alpha2A-AR; alpha-2AAR subtype C10; alpha-2-adrenergic receptor, platelet type; alpha2-C10; alpha-2D adrenergic receptor; AW122659; CA2-47; OTTHUMP00000058849; RATRG20; RG20; subtype alpha2-C10; ZNF32

more info or order :

Invitrogen product webpage