FKBP5 Polyclonal Antibody | Invitrogen PA1-020 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FKBP5 Polyclonal Antibody

catalog :

PA1-020

quantity :

100 µg

price :

US 430

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Chinese hamsters, human, mouse, rat, dogs

application :

western blot

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:1000; loading ...; fig 6a	Kalyan Masih P, Vega Torres J, Miles C, Haddad E, Rainsbury S, Baghchechi M, et al. Western High-Fat Diet Consumption during Adolescence Increases Susceptibility to Traumatic Stress while Selectively Disrupting Hippocampal and Ventricular Volumes. Eneuro. 2016;3: pubmed
	Mandigo A, Shafi A, McCann J, Yuan W, Laufer T, Bogdan D, et al. Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer. Cancer Res. 2022;82:221-234 pubmed publisher
	Lu Y, Sareddy G, Wang J, Zhang Q, Tang F, Pratap U, et al. Neuron-Derived Estrogen is Critical for Astrocyte Activation and Neuroprotection of the Ischemic Brain. J Neurosci. 2020;: pubmed publisher
	Mazaira G, Echeverria P, Galigniana M. Nucleocytoplasmic shuttling of the glucocorticoid receptor is influenced by tetratricopeptide repeat-containing proteins. J Cell Sci. 2020;133: pubmed publisher
	Leonardi D, Anselmino N, Brandani J, Jaworski F, Paez A, Mazaira G, et al. Heme Oxygenase 1 Impairs Glucocorticoid Receptor Activity in Prostate Cancer. Int J Mol Sci. 2019;20: pubmed publisher
	Bernadotte A, Kumar R, Winblad B, Pavlov P. In silico identification and biochemical characterization of the human dicarboxylate clamp TPR protein interaction network. FEBS Open Bio. 2018;8:1830-1843 pubmed publisher
	Harrell C, Rowson S, Neigh G. Pharmacological stimulation of hypoxia inducible factor-1Î± facilitates the corticosterone response to a mild acute stressor. Neurosci Lett. 2015;600:75-9 pubmed publisher

image

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product information

Product Type :

Antibody

Product Name :

FKBP5 Polyclonal Antibody

Catalog # :

PA1-020

Quantity :

100 µg

Price :

US 430

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Canine, Hamster, Human, Mouse, Rat

Applications :

Western Blot: 1-2 µg/mL

Species :

Canine, Hamster, Human, Mouse, Rat

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

FKBP5 is a member of the immunophilin protein family. This family plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP5 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. The gene that encodes FKBP5 has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Immunogen :

Synthetic peptide corresponding to the residues C(394) Q K K A K E H N E R D R R(407) of human FKBP51.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1-2 µg/mL

Aliases :

51 kDa FK506-binding protein; 51 kDa FKBP; 54 kDa progesterone receptor-associated immunophilin; AIG6; Androgen-regulated protein 6; D17Ertd592e; Dit1; EC 5.2.1.8; FF1 antigen; FK506 binding protein 5; FK506-binding protein 5; Fkbp5; FKBP-5; Fkbp51; FKBP-51; FKBP54; HSP90-binding immunophilin; p54; peptidylprolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP5; PPIase; PPIase FKBP5; Ptg-10; Rotamase; T-cell FK506-binding protein

more info or order :

Invitrogen product webpage