This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IL-6 Polyclonal Antibody
catalog :
P620
quantity :
1 mg
price :
US 440.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, flow cytometry
citations: 10
Reference
Ben Ammar R, Zahra H, Abu Zahra A, Alfwuaires M, Abdulaziz Alamer S, Metwally A, et al. Protective Effect of Fucoxanthin on Zearalenone-Induced Hepatic Damage through Nrf2 Mediated by PI3K/AKT Signaling. Mar Drugs. 2023;21: pubmed publisher
Zhazykbayeva S, Hassoun R, Herwig M, Budde H, Kov xe1 cs x, Mannherz H, et al. Oxidative stress and inflammation distinctly drive molecular mechanisms of diastolic dysfunction and remodeling in female and male heart failure with preserved ejection fraction rats. Front Cardiovasc Med. 2023;10:1157398 pubmed publisher
Woo J, Seo H, Lee J, Lee I, Jeon K, Kim B, et al. Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage. Part Fibre Toxicol. 2023;20:2 pubmed publisher
Luo J, Li J, Li T, Zhang Z, Chen G, Li Q, et al. PIAS1 Alleviates Hepatic Ischemia-Reperfusion Injury in Mice through a Mechanism Involving NFATc1 SUMOylation. Dis Markers. 2022;2022:4988539 pubmed publisher
Zhang S, Fan L, Wang Y, Xu J, Shen Q, Xie J, et al. Dihydromyricetin ameliorates osteogenic differentiation of human aortic valve interstitial cells by targeting c-KIT/interleukin-6 signaling pathway. Front Pharmacol. 2022;13:932092 pubmed publisher
de Z xe9 licourt A, Fayssoil A, Dakouane Giudicelli M, De Jesus I, Karoui A, Zarrouki F, et al. CD38-NADase is a new major contributor to Duchenne muscular dystrophic phenotype. EMBO Mol Med. 2022;14:e12860 pubmed publisher
Mohamed H, El Kamel A, Hammad G, Heikal L. Design of Targeted Flurbiprofen Biomimetic Nanoparticles for Management of Arthritis: In Vitro and In Vivo Appraisal. Pharmaceutics. 2022;14: pubmed publisher
Zhang H, Zhao J, Lu Q, Sun B, Liu X, Yang C, et al. Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways. Evid Based Complement Alternat Med. 2021;2021:1718709 pubmed publisher
Sohn M, Kang M, Kang S, Bae S. Downregulation of APRIN expression increases cancer cell proliferation via an interleukin-6/STAT3/cyclin D axis. Oncol Lett. 2021;21:55 pubmed publisher
Romberger D, Heires A, Nordgren T, Poole J, Toews M, West W, et al. β2-Adrenergic agonists attenuate organic dust-induced lung inflammation. Am J Physiol Lung Cell Mol Physiol. 2016;311:L101-10 pubmed publisher
product information
Product Type :
Antibody
Product Name :
IL-6 Polyclonal Antibody
Catalog # :
P620
Quantity :
1 mg
Price :
US 440.00
Clonality :
Polyclonal
Purity :
Protein G
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
ELISA: 1:50-1:5,000, Flow Cytometry: 1:50-1:200, Immunocytochemistry: 1:100, Western Blot: 1:1,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C
Description :
IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.
Immunogen :
Recombinant human IL-6.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:50-1:5,000, Flow Cytometry: 1:50-1:200, Immunocytochemistry: 1:100, Western Blot: 1:1,000
Aliases :
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA