TRPV4 Polyclonal Antibody | Invitrogen OST00146W product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRPV4 Polyclonal Antibody

catalog :

OST00146W

quantity :

100µL

price :

330 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

chicken

application :

western blot, immunohistochemistry

product information

Product Type :

Antibody

Product Name :

TRPV4 Polyclonal Antibody

Catalog # :

OST00146W

Quantity :

100µL

Price :

330 USD

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Chicken

Applications :

Immunohistochemistry: 1:300 - 1:2000, Western Blot: 1:300 - 1:2000

Species :

Chicken

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel, activated in response to systemic osmotic pressure. Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. TRPV4 is a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The TRPV4 protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in the TRPV4 gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Diseases associated with TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen :

A synthetic peptide from the 1t cytoplasmic loop of chicken TRPV4 (VRL-2, VRL2, OTRPC4, Vanilloid receptor-like channel 2) conjugated to an immunogenic carrier protein was used as the immunogen

Format :

Lyophilized

Applications w/Dilutions :

Immunohistochemistry: 1:300 - 1:2000, Western Blot: 1:300 - 1:2000

Aliases :

VRL-2, VRL2, OTRPC4, Vanilloid receptor-like channel 2